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Xiao-hong Cheng
Publications - 5
Citations - 35
Xiao-hong Cheng is an academic researcher. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 2, co-authored 2 publications receiving 14 citations.
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Journal ArticleDOI
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumor growth
Chunming Cheng,Feng Geng,Zoe Li,Yaogang Zhong,Huabao Wang,Xiang Cheng,Yue Zhao,Xiaokui Mo,Craig Horbinski,Wenrui Duan,Arnab Chakravarti,Xiao-hong Cheng,Deliang Guo +12 more
TL;DR: In this paper , the authors reveal that ammonia, released from glutamine, promotes lipogenesis via activation of sterol regulatory element-binding proteins (SREBPs), endoplasmic reticulum-bound transcription factors that play a central role in lipid metabolism.
Journal Article
Modulation of neuronal nicotinic acetylcholine receptors by glucocorticoids.
TL;DR: Coricosterone has rapid inhibitory effect on IACh, which indicates that corticosterone binds to the specific site on the outer cell membrane, probably on the neuronal nicotinic receptor-coupled channel, and inhibits the IACh in a noncompetitive manner, thus controlling the immediate catecholamine release from the sympathetic cells.
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Decrease in acetylcholine-induced current by neomycin in PC12 cells.
TL;DR: In this paper, the effects of neomycin, one of the aminoglycoside antibiotics, on the acetylcholine (ACh)-induced current (IACh) were studied in pheochromocytoma cells by using the whole-cell clamp technique.
Journal ArticleDOI
Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering.
TL;DR: In this paper , X-ray structures of human acetylcholinesterase (hAChE) with unaged paraoxon (POX) and oximes MMB4 and RS170B were reported.
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The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets.
Yulin Ren,Elizabeth N. Kaweesa,L. Tian,Sijin Wu,Kongmany Sydara,Mouachanh Xayvue,Curtis E. Moore,Djaja D. Soejarto,Xiao-hong Cheng,Jianhua Yu,Joanna E. Burdette,A. Douglas Kinghorn +11 more
TL;DR: A cardiac glycoside epoxide, (-)-cryptanoside A (1), was isolated from the stems of Cryptolepis dubia collected in Laos, for which the complete structure was confirmed by analysis of its spectroscopic and single-crystal X-ray diffraction data, using copper radiation at a low temperature as discussed by the authors .