Xiaofang Yi

TL;DR: It is reported that inhibition of NF-E2-related factor 2 (Nrf2) may be a promising strategy to combat chemoresistance, and evidence is provided that the strategy of using Nrf2 inhibitors to increase efficacy of chemotherapeutic agents is not limited to certain cancer types or anticancer drugs and thus can be applied during the course of chemotherapy to treat many cancer types.

TL;DR: It is concluded that expression of IMP3, a newly identified cytoplasmic marker, is closely associated with type II endometrial cancer and it seems that IMP3 expression is associated with an aggressive histologic phenotype amongendometrial neoplastic lesions.

TL;DR: The findings of the present study suggest that autophagy has a protective role in human ovarian cancer cells, and that targeting Autophagy may promote chemotherapeutic sensitivity.

TL;DR: In ovarian cancers, it is found that GAPDH expression is regulated, and it is recognized that one of the many functions of GAPDh is to promote mRNA stability of CSF-1, an important cytokine in tumor progression.

TL;DR: Data indicate that the novel NRF2 target gene,ABCF2, plays a critical role in cisplatin resistance in ovarian cancer, and that targeting ABCF2 may be a new strategy to improve chemotherapeutic efficiency.