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Xiaolei Liang
Researcher at Peking Union Medical College
Publications - 3
Citations - 529
Xiaolei Liang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Mesenchymal stem cell & Adipogenesis. The author has an hindex of 3, co-authored 3 publications receiving 386 citations.
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Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a
TL;DR: It is indicated that adMSC-Exo can transfer miR-125a to endothelial cells and promote angiogenesis by repressing DLL4 and repressed the expression of the angiogenic inhibitor delta-like 4 by targeting its 3′ untranslated region.
Journal ArticleDOI
let-7 Enhances Osteogenesis and Bone Formation While Repressing Adipogenesis of Human Stromal/Mesenchymal Stem Cells by Regulating HMGA2
Jianfeng Wei,Hongling Li,Shihua Wang,Tangping Li,Junfen Fan,Xiaolei Liang,Jing Li,Qin Han,Li Zhu,Linyuan Fan,Robert Chunhua Zhao +10 more
TL;DR: A novel role of let-7/HMGA2 axis is found in regulating the balance of osteogenesis and adipogenesis of MSCs and can be used as a novel therapeutic target for disorders that are associated with bone loss and adipocyte accumulation.
Journal ArticleDOI
MicroRNA-498 Inhibition Enhances the Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Podocyte-Like Cells
Lina Zhang,Kanghua Li,Xi Yan,Xiaolei Liang,Shihua Wang,Qin Han,Robert Chunhua Zhao,Robert Chunhua Zhao +7 more
TL;DR: This study advocated an efficient method for the induction of kidney podocyte-like (iPod) cells from hAD-MSCs and provided an ideal candidate for regenerative therapies of the kidney.