Xiaoyun Wang

TL;DR: This report investigated whether inhaled EXOs serve as an efficient and practical delivery vehicle to activate or inhibit alveolar macrophages, subsequently modulating pulmonary immune responses, and developed a novel protocol using serum-derived EXOs to deliver designated small RNA molecules into lung macrophage in vivo, potentially shedding light on future gene therapy of human lung diseases.

TL;DR: In the pathogenesis of lung macrophage-mediated inflammatory responses, MV-miR-223/142 secretion is robustly enhanced and detectable in BALF and serum.

TL;DR: It is suggested that downregulation of p38-mediated miR-1/133 expression by FGF2 and subsequent upregulation of Sp1/Cyclin D1 contribute to the increased myoblast proliferation during the early stage of muscle regeneration.

TL;DR: The results suggest that the interplay between miR-182 and Hif1α could result in a sustained activation of HIF1α pathway, which might facilitate tumor cell adaption to hypoxic stress during prostate tumor progression.

TL;DR: Thyroid hormone promotes slow-to-fast muscle fiber type conversion by inducing miR-133a1 and thereby repressing the expression of the slow muscle determinant TEAD1.