L
Lokesh Sharma
Researcher at Yale University
Publications - 95
Citations - 4810
Lokesh Sharma is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 22, co-authored 73 publications receiving 3301 citations. Previous affiliations of Lokesh Sharma include St. John's University & The Feinstein Institute for Medical Research.
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Journal ArticleDOI
Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19)
Li Guo,Lili Ren,Siyuan Yang,Meng Xiao,De Chang,Fan Yang,Charles S. Dela Cruz,Yingying Wang,Chao Wu,Yan Xiao,Lulu Zhang,Lianlian Han,Shengyuan Dang,Yan Xu,Qi Wen Yang,Sheng Yong Xu,Hua Dong Zhu,Yingchun Xu,Qi Jin,Lokesh Sharma,Linghang Wang,Jianwei Wang +21 more
TL;DR: The humoral response to SARS-CoV-2 can aid in the diagnosis of COVID-19, including subclinical cases, and the detection efficiency by IgM ELISA is higher than that of qPCR after 5.5 days of symptom onset.
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Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China.
TL;DR: This case series uses patient hospital data to summarize the clinical presentation and laboratory and imaging findings of 13 patients with confirmed 2019-nCoV infection admitted to hospitals in Beijing in January 2020.
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Protecting health-care workers from subclinical coronavirus infection.
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Mechanosensation of Cyclical Force by PIEZO1 is Essential for Innate Immunity
Angel G. Solis,Piotr Bielecki,Holly R. Steach,Lokesh Sharma,Christian C. D. Harman,Sanguk Yun,Marcel R. de Zoete,James N. Warnock,S. D. Filip To,Autumn G. York,Matthias Mack,Martin A. Schwartz,Charles S. Dela Cruz,Noah W. Palm,Ruaidhri Jackson,Richard A. Flavell,Richard A. Flavell +16 more
TL;DR: The results reveal an environmental sensory axis that stimulates innate immune cells to mount an inflammatory response, and demonstrate a physiological role for PIEZO1 and mechanosensation in immunity.
Journal ArticleDOI
Time Kinetics of Viral Clearance and Resolution of Symptoms in Novel Coronavirus Infection.
De Chang,Guoxin Mo,Xin Yuan,Yi Tao,Xiaohua Peng,Fu-Sheng Wang,Lixin Xie,Lokesh Sharma,Charles S. Dela Cruz,Enqiang Qin +9 more
TL;DR: This data indicates that coronavirus infection in animals is a major cause of death in people infected withCoronavirus, and the use of antibiotics to treat these infections is a natural application.