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Xin Hu
Researcher at Chiba University
Publications - 5
Citations - 182
Xin Hu is an academic researcher from Chiba University. The author has contributed to research in topics: Apoptosis & Abscopal effect. The author has an hindex of 4, co-authored 5 publications receiving 160 citations.
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Journal ArticleDOI
MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer
Naoki Akanuma,Isamu Hoshino,Yasunori Akutsu,Kentarou Murakami,Yuka Isozaki,Tetsurou Maruyama,Gulbostan Yusup,Wei Qin,Takeshi Toyozumi,Masahiko Takahashi,Hiroshi Suito,Xin Hu,Nobufumi Sekino,Hiromasa Matsubara +13 more
TL;DR: The combined expression of FSCN1 and MMP14 is associated with a poor prognosis, and miR-133a, which regulates their mRNAs, can serve as a strong tumour suppressor of ESCC.
Journal ArticleDOI
Modulated electro-hyperthermia enhances dendritic cell therapy through an abscopal effect in mice
Wei Qin,Yasunori Akutsu,Gabor Andocs,Akiko Suganami,Xin Hu,Gulbostan Yusup,Aki Komatsu-Akimoto,Isamu Hoshino,Naoyuki Hanari,Mikito Mori,Yuka Isozaki,Naoki Akanuma,Yutaka Tamura,Hisahiro Matsubara +13 more
TL;DR: Results indicated that the combination therapy of an intratumoral DC injection and mEHT evoked systemic antitumor activity and the effect of immunotherapy with DCs was strongly enhanced by the overexpression of GP96, thought to be one of the molecules explaining the abscopal effect.
Journal ArticleDOI
A COX-2 inhibitor enhances the antitumor effects of chemotherapy and radiotherapy for esophageal squamous cell carcinoma.
Gulbostan Yusup,Yasunori Akutsu,Muradil Mutallip,Wei Qin,Xin Hu,Aki Komatsu-Akimoto,Isamu Hoshino,Naoyuki Hanari,Mikito Mori,Naoki Akanuma,Yuka Isozaki,Hisahiro Matsubara +11 more
TL;DR: The experiments showed that T.Tn and TE2 proliferation was strongly inhibited by the combination of 5-FU/radiation and the COX-2 inhibitor, which can be useful enhancers of antitumor drugs and radiotherapy for ESCC.
Journal ArticleDOI
Low-dose hyperthermia enhances the antitumor effects of chemotherapy in squamous cell carcinoma.
Xin Hu,Yasunori Akutsu,Akiko Suganami,Wei Qin,Naoyuki Hanari,K Murakam,Masayuki Kano,Akihiro Usui,Hiroshi Suito,Masahiko Takahashi,Yasunori Matsumoto,R Otsuta,Yutaka Tamura,Hiromasa Matsubara +13 more
TL;DR: Low-dose hyperthermia (LDH) may be a useful enhancer of chemotherapy drugs for squamous cell carcinoma and can result in much higher efficacy of antitumor drugs.
Journal ArticleDOI
The effect of stress on efficacy of dendritic cell therapy for esophageal squamous cell carcinoma.
Yasunori Akutsu,Wei Qin,Kentaro Murakami,Isamu Hoshino,Naoyuki Hanari,Takanori Nishimori,Mikito Mori,Yuka Isozaki,Takeshi Toyozumi,Xin Hu,Hiroshi Suito,Naoki Akanuma,Masahiko Takahashi,Hisahiro Matsubara +13 more
TL;DR: The enhancement of dendritic cell (DC) therapy by various stress, such as radiation or modulated electro-hyperthermia (mEHT) in DC therapy for squamous cell carcinoma (SCC) was tested.