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Xinyong Chen

Researcher at University of Nottingham

Publications -  72
Citations -  3577

Xinyong Chen is an academic researcher from University of Nottingham. The author has contributed to research in topics: Polymer & Surface plasmon resonance. The author has an hindex of 30, co-authored 70 publications receiving 3365 citations.

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Comparison of calibration methods for atomic-force microscopy cantilevers

TL;DR: In this paper, the authors compared the experimentally determined values of stiffness for ten cantilever probes using four different methods, based on the acquisition and analysis of thermal distribution functions of the oscillator's amplitude fluctuations.
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Substrate stiffness affects early differentiation events in embryonic stem cells.

TL;DR: A fundamental role for mechanosensing in mammalian development is suggested and the mechanical environment should be taken into consideration when engineering implantable scaffolds or when producing therapeutically relevant cell populations in vitro is illustrated.
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Detection of antigen-antibody binding events with the atomic force microscope.

TL;DR: An atomic force microscope has been used to directly monitor specific interactions between antibodies and antigens employed in an immunoassay system, and analysis of the force distribution data suggests a quantization of the forces.
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Characterization of the surfaces generated by liposome binding to the modified dextran matrix of a surface plasmon resonance sensor chip

TL;DR: The dextran matrix of a surface plasmon resonance (SPR) sensor chip modified with hydrophobic residues (BIAcore sensor chip L1) provides an ideal substrate for liposome adsorption and atomic force microscopy (AFM) and fluorescence microscopy investigated these materials, indicating that the liposomes fuse and form a lipid bilayer on the dextrans matrix.