X
Xinyong Chen
Researcher at University of Nottingham
Publications - 72
Citations - 3577
Xinyong Chen is an academic researcher from University of Nottingham. The author has contributed to research in topics: Polymer & Surface plasmon resonance. The author has an hindex of 30, co-authored 70 publications receiving 3365 citations.
Papers
More filters
Journal ArticleDOI
Comparison of calibration methods for atomic-force microscopy cantilevers
Nancy A. Burnham,Xinyong Chen,C S Hodges,G A. Matei,E. J. Thoreson,Clive J. Roberts,Martyn C. Davies,Saul J. B. Tendler +7 more
TL;DR: In this paper, the authors compared the experimentally determined values of stiffness for ten cantilever probes using four different methods, based on the acquisition and analysis of thermal distribution functions of the oscillator's amplitude fluctuations.
Journal ArticleDOI
Substrate stiffness affects early differentiation events in embryonic stem cells.
Nicholas D. Evans,Caterina Minelli,Eileen Gentleman,Vanessa L.S. LaPointe,Sameer N. Patankar,Maria Kallivretaki,Xinyong Chen,Clive J. Roberts,Molly M. Stevens +8 more
TL;DR: A fundamental role for mechanosensing in mammalian development is suggested and the mechanical environment should be taken into consideration when engineering implantable scaffolds or when producing therapeutically relevant cell populations in vitro is illustrated.
Journal ArticleDOI
Detection of antigen-antibody binding events with the atomic force microscope.
Stephanie Allen,Xinyong Chen,J. M. Davies,Martyn C. Davies,Dawkes Adrian Charles,J. C. Edwards,Clive J. Roberts,Joanna Sefton,Saul J. B. Tendler,Philip M. Williams +9 more
TL;DR: An atomic force microscope has been used to directly monitor specific interactions between antibodies and antigens employed in an immunoassay system, and analysis of the force distribution data suggests a quantization of the forces.
Journal ArticleDOI
Characterization of the surfaces generated by liposome binding to the modified dextran matrix of a surface plasmon resonance sensor chip
Eva-Maria Erb,Xinyong Chen,Stephanie Allen,Clive J. Roberts,Saul J. B. Tendler,Martyn C. Davies,Sture Forsén +6 more
TL;DR: The dextran matrix of a surface plasmon resonance (SPR) sensor chip modified with hydrophobic residues (BIAcore sensor chip L1) provides an ideal substrate for liposome adsorption and atomic force microscopy (AFM) and fluorescence microscopy investigated these materials, indicating that the liposomes fuse and form a lipid bilayer on the dextrans matrix.
Journal ArticleDOI
Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity
Leanne E. Fisher,Andrew L. Hook,Waheed Ashraf,Anfal Yousef,David A. Barrett,David J. Scurr,Xinyong Chen,Emily F. Smith,Michael W. Fay,Christopher D. J. Parmenter,Richard Parkinson,Roger Bayston +11 more
TL;DR: The antimicrobial catheter offers for the first time a means of reducing infection and its complications in long-term urinary catheter users.