Xionghui Mao

TL;DR: MTT and lactate dehydrogenase (LDH) assays indicated that three acidic polysaccharides, namely LSPb1, L SPb2 and LSPc1, possessed more potent antiproliferative effect on human laryngocarcinoma Hep-2 cells than neutral poly Saccharide LSPa1 in a dose- and time-dependent manner.

TL;DR: It is found that HPV+HNSCC exosomes were able to transform macrophages into the M1 phenotype, which subsequently increased the radiosensitivity of HNSCC, and miR-9 may be used as a potential treatment for H NSCC.

TL;DR: Meng et al. as discussed by the authors explored the biological effects of miR-217 on laryngeal cancer and found that miR217 inhibited multiple metastatic traits, including cell migration, invasion, proliferation, apoptosis, and EMT, as well as angiogensis.

TL;DR: M1 macrophages represent an important tissue microenvironment factor with implications for HNSC treatment efficacy and may prove valuable as a biomarker of radiation sensitivity.

TL;DR: The results suggest that AFAP1‐AS1 can serve as a prognostic biomarker in laryngeal carcinoma and that miR‐320a has the potential to improve standard therapeutic approaches to the disease, especially for cases in which cancer cell stemness and drug resistance present significant barriers to effective treatment.