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Xiu-Ping Wang
Researcher at University of Helsinki
Publications - 10
Citations - 1307
Xiu-Ping Wang is an academic researcher from University of Helsinki. The author has contributed to research in topics: Mesenchyme & Fibroblast growth factor. The author has an hindex of 10, co-authored 10 publications receiving 1232 citations. Previous affiliations of Xiu-Ping Wang include Brigham and Women's Hospital.
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Journal ArticleDOI
Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar
Johanna Laurikkala,Johanna Pispa,Han Sung Jung,Pekka Nieminen,Marja L. Mikkola,Xiu-Ping Wang,Ulpu Saarialho-Kere,Juan Galceran,Rudi Grosschedl,Irma Thesleff +9 more
TL;DR: It is suggested that Eda and Edar are associated with the onset of ectodermal patterning and that ectodysplasin/edar signaling also regulates the morphogenesis of hair follicles.
Journal ArticleDOI
An Integrated Gene Regulatory Network Controls Stem Cell Proliferation in Teeth
Xiu-Ping Wang,Marika Suomalainen,Szabolcs Felszeghy,Laura C Zelarayan,Maria Teresa Alonso,Maxim V. Plikus,Richard L. Maas,Cheng-Ming Chuong,Thomas Schimmang,Irma Thesleff +9 more
TL;DR: It is shown how the spatially restricted and balanced effects of specific components of a signaling network can regulate stem cell proliferation in the niche and account for asymmetric organogenesis.
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Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood
Xiu-Ping Wang,Daniel J. O’Connell,Jennifer J. Lund,Irfan Saadi,Mari Kuraguchi,Annick Turbe-Doan,Resy Cavallesco,Hyun-Chul Kim,Peter J. Park,Hidemitsu Harada,Raju Kucherlapati,Raju Kucherlapati,Richard L. Maas +12 more
TL;DR: It is shown that supernumerary teeth can form from multiple regions of the jaw and that they are properly mineralized, vascularized, innervated and can start to form roots.
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Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis.
Thomas Åberg,Xiu-Ping Wang,Jung Hwan Kim,Takashi Yamashiro,Marianna Bei,Ritva Rice,Hyun-Mo Ryoo,Irma Thesleff +7 more
TL;DR: It is concluded that Runx2 mediates the functions of epithelial FGF signals regulating F gf3 expression in the dental mesenchyme and that Fgf3 may be a direct target gene of Runx 2.
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Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis.
Mitsushiro Nakatomi,Xiu-Ping Wang,Darren Key,Jennifer J. Lund,Annick Turbe-Doan,Ralf Kist,Andrew Aw,YiPing Chen,Richard L. Maas,Heiko Peters +9 more
TL;DR: A combined reduction of PAX9 and MSX1 gene dosage in humans may increase the risk for orofacial clefting and oligodontia and the data suggest that Msx1 and Pax9 interact synergistically throughout lower incisors development and affect multiple signaling pathways that influence incisor size and symmetry.