Xiuhua Yang

TL;DR: Findings indicate that TNF-alpha up-regulates angiogenic factor expression in MG cells and that RNA stabilization, via the AREs in the 3'-untranslated region, contributes to this up-regulation.

TL;DR: Findings reveal a HuR-dependent mechanism for cancer cell survival and sensitivity to chemotherapeutic drugs suggesting that HuR should be considered as a new therapeutic target.

TL;DR: Findings indicate that PRMT5 is a marker of malignant progression in glioma tumors and plays a pivotal role in tumor growth.

TL;DR: Results suggest that SFKs represent an effective target for GSC migration but not for their growth, and Knockdown of c-Src, Yes or treatment with the SFK inhibitor dasatinib inhibited the migration of GSCs, but had no impact on their growth or self-renewal.

TL;DR: It is proposed that HuR stores mRNA in the centrosome and thatHuR phosphorylation by Cdk5 controls de novo protein synthesis in near proximity to centrosomes and, thus, impactsCentrosome function.