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Xiyi Lu
Researcher at Nanjing Medical University
Publications - 19
Citations - 676
Xiyi Lu is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 10 publications receiving 439 citations.
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Journal ArticleDOI
A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1
Erbao Zhang,Xuezhi He,Chongguo Zhang,Jun Su,Xiyi Lu,Xinxin Si,Jinfei Chen,Dandan Yin,Liang Han,Liang Han,Wei De +10 more
TL;DR: The data demonstrate that abnormal histone modification-activated HOXC-AS3 may play important roles in gastric cancer oncogenesis and may serve as a target for Gastric cancer diagnosis and therapy.
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Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non-small cell lung cancer cell proliferation by epigenetically repressing p21 expression.
TL;DR: Mechanistic investigations found that AFAP1-AS1 could interact with EZH2 and recruit EZh2 to the promoter regions of p21, thus epigenetically repressing p21 expression and suggesting that lncRNA AFAP 1- AS1 may serve as a candidate prognostic biomarker and target for new therapies in human NSCLC.
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LINC00665 Induces Acquired Resistance to Gefitinib through Recruiting EZH2 and Activating PI3K/AKT Pathway in NSCLC.
Xinyin Liu,Xiyi Lu,Fuxi Zhen,Shidai Jin,Tongfu Yu,Quan Zhu,Wei Wang,Kun Xu,Jiaqi Yao,Renhua Guo +9 more
TL;DR: The study suggests that long intergenic non-coding RNA 00665 is important for non-small-cell lung cancer to develop drug resistance and might be a potential biomarker for drug resistance
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Long non-coding RNA LUCAT1 is associated with poor prognosis in human non-small cell lung cancer and regulates cell proliferation via epigenetically repressing p21 and p57 expression
TL;DR: The expression of LUCAT1 was significantly up-regulated in NSCLC tissues compared to non-tumor tissues, and its expression was associated with tumor size, tumor–node–metastasis stage and overall survival (OS).
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A Novel Long Non-Coding RNA, SOX21-AS1, Indicates a Poor Prognosis and Promotes Lung Adenocarcinoma Proliferation.
TL;DR: It is demonstrated that SOX21-AS1 is involved in the development and progression of LUAD and that SOx21-as1 may be a potential diagnostic factor as well as a target for new therapies for patients with LUAD.