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Xuezhi He
Researcher at Nanjing Medical University
Publications - 30
Citations - 1798
Xuezhi He is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Long non-coding RNA & Gene knockdown. The author has an hindex of 18, co-authored 24 publications receiving 1420 citations.
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Journal ArticleDOI
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma.
Erbao Zhang,Liang Han,Dandan Yin,Xuezhi He,Linzhi Hong,Xinxin Si,Mantang Qiu,Tongpeng Xu,Wei De,Lin Xu,Yongqian Shu,Jinfei Chen +11 more
TL;DR: RNA-seq analysis revealed that CCAT1 knockdown preferentially affected genes that are linked to cell proliferation, cell migration and cell adhesion, and demonstrated the important roles ofCCAT1 in ESCC oncogenesis and might serve as targets for ESCC diagnosis and therapy.
Journal ArticleDOI
A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1
Erbao Zhang,Xuezhi He,Chongguo Zhang,Jun Su,Xiyi Lu,Xinxin Si,Jinfei Chen,Dandan Yin,Liang Han,Liang Han,Wei De +10 more
TL;DR: The data demonstrate that abnormal histone modification-activated HOXC-AS3 may play important roles in gastric cancer oncogenesis and may serve as a target for Gastric cancer diagnosis and therapy.
Journal ArticleDOI
Long noncoding RNA GAS5 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer
TL;DR: The results suggest that GAS5, as a growth regulator, may serve as a candidate prognostic biomarker in human colorectal cancer.
Journal ArticleDOI
Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57.
Erbao Zhang,Xuezhi He,Dandan Yin,Liang Han,Mantang Qiu,Tongpeng Xu,Rui Xia,Lei Xu,Rong Yin,Wei De +9 more
TL;DR: It is found that TUG1 is significantly increased and is correlated with outcomes in gastric cancer (GC) and further experiments revealed that knockdown of Tug1 repressed GC proliferation both in vitro and in vivo.
Journal ArticleDOI
Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression.
Jie Ding,Juan Li,HaiYan Wang,Yun Tian,Min Xie,Xuezhi He,Hao Ji,Zhonghua Ma,Bingqing Hui,Keming Wang,Guozhong Ji +10 more
TL;DR: The data suggest that the lncRNA CRNDE promotes the progression of CRC and is a potential therapeutic target for CRC intervention.