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Xu D. Zhang
Researcher at University of Newcastle
Publications - 2
Citations - 165
Xu D. Zhang is an academic researcher from University of Newcastle. The author has contributed to research in topics: Unfolded protein response & Gene expression. The author has an hindex of 2, co-authored 2 publications receiving 148 citations.
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Journal ArticleDOI
P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation
Kelly A. Avery-Kiejda,Nikola A. Bowden,Amanda Croft,Lyndee L. Scurr,Carla F. Kairupan,Katie A. Ashton,Bente A. Talseth-Palmer,Helen Rizos,Xu D. Zhang,Rodney J. Scott,Peter Hersey +10 more
TL;DR: It is indicated that P53 target genes involved in apoptosis and cell cycle regulation are aberrantly expressed in melanoma and that this aberrant functional activity of P53 may contribute to the proliferation of melanoma.
Journal ArticleDOI
Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress
Amanda Croft,Amanda Croft,Kwang H. Tay,Suzanah C. Boyd,Su T. Guo,Chen C. Jiang,Fritz Lai,Hsin-Yi Tseng,Lei Jin,Helen Rizos,Peter Hersey,Xu D. Zhang +11 more
TL;DR: Results reveal that potentiation of adaptation to chronic ER stress is another mechanism by which oncogenic activation of the MEK/ERK pathway promotes the pathogenesis of melanoma.