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Xue Yao
Researcher at Nankai University
Publications - 10
Citations - 189
Xue Yao is an academic researcher from Nankai University. The author has contributed to research in topics: Bovine immunodeficiency virus & Integrase. The author has an hindex of 5, co-authored 10 publications receiving 160 citations. Previous affiliations of Xue Yao include Chinese Ministry of Education.
Papers
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Journal ArticleDOI
Design, synthesis and antiviral activity of novel quinazolinones.
Ziwen Wang,Mingxiao Wang,Xue Yao,Yue Li,Juan Tan,Lizhong Wang,Wentao Qiao,Yunqi Geng,Yuxiu Liu,Qingmin Wang +9 more
TL;DR: A series of quinazolinones were designed and synthesized as novel HIV-1 inhibitors and found to exhibit good anti-TMV activity, of which compo und 9a showed similar in vivo anti- TMV activity to commercial plant virucide Ribavirin.
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Hydroxyl may not be indispensable for raltegravir: Design, synthesis and SAR Studies of raltegravir derivatives as HIV-1 inhibitors.
TL;DR: The 5-hydroxyl modification of raltegravir derivatives significantly increased the anti-HIV activity, which indicates that the hydroxyl may not be indispensable for ralTeGravir, and these compounds may be considered as new potent anti-hIV agents.
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Design, synthesis and antiviral activity of novel pyridazines.
Ziwen Wang,Mingxiao Wang,Xue Yao,Yue Li,Juan Tan,Lizhong Wang,Wentao Qiao,Yunqi Geng,Yuxiu Liu,Qingmin Wang +9 more
TL;DR: A series of pyridazines were prepared and evaluated for their anti-HIV activity, and the new synthetic route involving a novel rearrangement reaction provided a practical method for the preparation of 5-hydroxypyridazine.
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Hydroxyl May Not Be Indispensable for Raltegravir: Design, Synthesis and SAR Studies of Raltegravir Derivatives as HIV-1 Inhibitors.
TL;DR: A variety of raltegravir derivatives such as (I) and (II) is synthesized and systematically evaluated for their anti-HIV activity.
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Bovine ISG15: an antiviral and inducible protein in BIV infected fetal bovine lung cells
TL;DR: It is demonstrated that bISG15 plays an important role in inhibition of the BIV replication in FBL cells and real-time PCR and western blot assay revealed that b ISG15's expression can also be induced in BIV infected F BL cells.