Y
Yan Yang
Publications - 2
Citations - 29
Yan Yang is an academic researcher. The author has contributed to research in topics: Inflammation & Cytokine. The author has an hindex of 2, co-authored 2 publications receiving 15 citations.
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A new anti-HER2 antibody that enhances the anti-tumor efficacy of trastuzumab and pertuzumab with a distinct mechanism of action
Xuesai Zhang,Chen Jianhe,Zhibing Weng,Li Qingrou,Le Zhao,Ning Yu,Lan Deng,Wei Xu,Yan Yang,Zhu Zhenping,Haomin Huang +10 more
TL;DR: A new anti-HER2 humanized monoclonal antibody, 19H6-Hu, which binds to HER2 extracellular domain (ECD) with high affinity and inhibits proliferation of multiple HER2-overexpressing cancer cell lines as a single agent or in combination with trastuzumab.
Journal ArticleDOI
Important roles of CD32 in promoting suppression of IL-4 induced immune responses by a novel anti-IL-4Rα therapeutic antibody.
Zhao Jie,Jiang Liangfeng,Lan Deng,Wei Xu,Yang Cao,Chen Chen,Yan Yang,Wu Huiling,Huang Yuping,Zhenping Zhu,Haomin Huang +10 more
TL;DR: A novel humanized anti-IL-4Rα antibody is developed that can potently inhibit IL-4/IL-13-mediated TF-1 cell proliferation and provides new insights into designing therapeutic antibodies for targeting Th2 cytokine-mediated allergic pathogenesis.