Y
Yanbin Chen
Researcher at Soochow University (Suzhou)
Publications - 2
Citations - 44
Yanbin Chen is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Kinase activity & P70-S6 Kinase 1. The author has an hindex of 2, co-authored 2 publications receiving 31 citations.
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Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes.
Shinichi Oka,Tsuyoshi Hirata,Wataru Suzuki,Daichi Naito,Yanbin Chen,Adave Chin,Hiroaki Yaginuma,Toshiro Saito,Narayani Nagarajan,Peiyong Zhai,Santosh Bhat,Kevin Schesing,Dan Shao,Yoko Hirabayashi,Junji Yodoi,Sebastiano Sciarretta,Junichi Sadoshima +16 more
TL;DR: The results suggest that Trx1 protects cardiomyocytes against stress by reducing mTOR at Cys-1483, thereby preserving the activity of mTOR and inhibiting cell death.
Journal ArticleDOI
Ser9 phosphorylation of GSK-3β promotes aging in the heart through suppression of autophagy
Yanbin Chen,Yasuhiro Maejima,Akihiro Shirakabe,Takanobu Yamamoto,Yoshiyuki Ikeda,Junichi Sadoshima,Peiyong Zhai +6 more
TL;DR: The results suggest that GSK-3β is inactivated during aging through Ser9 phosphorylation, which in turn plays an important role in mediating cardiac aging.