다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

Wounds are one of the most common health issues, and the cost of wound care and healing has continued to increase over the past decade. The first step in wound healing is haemostasis, and the development of haemostatic materials that aid wound healing has accelerated in the past 5 years. Numerous haemostatic materials have been fabricated, composed of different active components (including natural polymers, synthetic polymers, silicon-based materials and metal-containing materials) and in various forms (including sponges, hydrogels, nanofibres and particles). In this Review, we provide an overview of haemostatic materials in wound healing, focusing on their chemical design and operation. We describe the physiological process of haemostasis to elucidate the principles that underpin the design of haemostatic wound dressings. We also highlight the advantages and limitations of the different active components and forms of haemostatic materials. The main challenges and future directions in the development of haemostatic materials for wound healing are proposed. Uncontrolled bleeding is a major cause of death, incentivizing the development of biomaterials that aid haemostasis and wound healing. This Review highlights the active components and forms of haemostatic materials, with a focus on their chemical design, and considers future trends in their development.

Haemostatic materials for wound healing applications

Mussel-inspired adhesive antioxidant antibacterial hemostatic composite hydrogel wound dressing via photo-polymerization for infected skin wound healing.

Mussel-inspired adhesive antioxidant antibacterial hemostatic composite hydrogel wound dressing via photo-polymerization for infected skin wound healing

Biofilm-inspired adhesive and antibacterial hydrogel with tough tissue integration performance for sealing hemostasis and wound healing

The invention discloses a polyglutamic acid gel micrococcus agent.A microorganism, a glycidyl methacrylate modified gama-polyglutamic acid, a photoinitiator, and water are used as dispersion phases, ahexadecane and a span 80 are used as continuous phases, droplet-based microfluidics technology is adopted to prepare microspheres, the sizes of themicrospheresare between 100 to 500 [mu]m. The invention further discloses preparation method and application of the polyglutamic acid gel micrococci agent. According to the polyglutamic acid gel microspheres,anembedding microbial agent can be released,the effective period of the high effective viable count can be prolonged, high activity biological function is realized, colonization of the functional microbial agent in the soil is advantageous, avariety of crop diseasescan be effectivelyprevented and controlled, the using amounts of chemical pesticides and chemical fertilizers are decreased, biological control and chemical control areeffectively combined, strengths are taken to offset weaknesses, integrated crop prevention and control is realized, and time and effort are saved.

Polyglutamic acid gel micrococcusagent and application thereof

The invention discloses an agricultural microbial agent microcapsule based on cell membrane mimicking and a preparation method thereof. The effect of regulating the osmotic pressure of cells is realized by regulating the moisture content of microbial cells and the flux of oxygen; and the wall material of the microcapsule is selected from gamma-polyglutamic acid (gamma-PGA), a polysaccharide material and dopamine. The gamma-PGA can achieve a synergistic effect with a microbial agent so as to enhance the antioxidant ability of plants, alleviate damage to plants under abiotic stress and promote plant growth, and is a typical microorganism-derived biostimulant; and a compact film formed by auto-polymerization of the dopamine on the surfaces of bacteria can effectively relieve the influence ofexternal osmotic pressure on the bacteria in the microcapsule, and polymerization reaction conditions are mild and have small damage to the bacteria. The preparation method disclosed by the inventionis based on a cell surface polymerization technology, and can realize single-cell coating of the microbial agent and inhibit proliferation of the microbial agent.

Yang Kai

Papers

Biofilm-inspired adhesive and antibacterial hydrogel with tough tissue integration performance for sealing hemostasis and wound healing

Polyglutamic acid gel micrococcusagent and application thereof

Agricultural microbial agent microcapsule based on cell membrane mimicking and preparation method thereof