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Yangfeng Li
Researcher at Chongqing University
Publications - 3
Citations - 43
Yangfeng Li is an academic researcher from Chongqing University. The author has contributed to research in topics: DNA & Antibody. The author has an hindex of 1, co-authored 3 publications receiving 3 citations.
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Strategies for targeting undruggable targets.
TL;DR: The concept of undruggable targets was introduced in this article, which refers to clinically meaningful therapeutic targets that are "difficult to drug" or "yet to be drugged" via traditional approaches.
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Second-generation DNA-encoded multiple display on a constant macrocyclic scaffold enabled by an orthogonal protecting group strategy
TL;DR: This work developed a novel strategy which utilized four orthogonal amine-protecting groups on DNA, to explore larger chemical combinations on the same constant macrocyclic scaffold, following the parallel paradigm to mimic the versatile antibody-like multivalent epitope recognition patterns.
Journal ArticleDOI
Sequential DNA-Encoded Building Block Fusion for the Construction of Polysubstituted Pyrazoline Core Libraries.
TL;DR: A sequential DNA-encoded synthesis strategy for polysubstituted pyrazoline heterocycles, which fuses a broad panel of aldehydes, aryl amines, and alkenes as building blocks, was presented in this paper.