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Yanjie Zhao

Researcher at Capital Medical University

Publications -  20
Citations -  226

Yanjie Zhao is an academic researcher from Capital Medical University. The author has contributed to research in topics: Immunotherapy & Breast cancer. The author has an hindex of 6, co-authored 20 publications receiving 149 citations.

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Journal ArticleDOI

Overexpression of an Immune Checkpoint (CD155) in Breast Cancer Associated with Prognostic Significance and Exhausted Tumor-Infiltrating Lymphocytes: A Cohort Study.

TL;DR: Overexpression of CD155 was correlated with more proliferative cancer cells and a dysfunctional immune microenvironment, and might be a potential immunotherapy target for breast cancer.
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Immune correlates of clinical benefit in a phase I study of hyperthermia with adoptive T cell immunotherapy in patients with solid tumors.

TL;DR: Combining HT with ACT plus either CT or anti-PD-1 antibody was safe, generated clinical responses in previously treated advanced cancers, and promoted TCR repertoire diversity and favorable changes in serum IL-2, IL-4, TNF-α, and IFN-γ levels in clinical responders.
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Continuous DC-CIK infusions restore CD8+ cellular immunity, physical activity and improve clinical efficacy in advanced cancer patients unresponsive to conventional treatments.

TL;DR: In advanced cancer patients, continuous dendritic cell-cytokine induced killer cell infusions are capable of recovering cellular immunity, improving patient status and quality of life in those who are unresponsive to conventional cancer treatment.