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Yanmei Huang
Researcher at Sichuan University
Publications - 25
Citations - 338
Yanmei Huang is an academic researcher from Sichuan University. The author has contributed to research in topics: Human serum albumin & Docking (molecular). The author has an hindex of 11, co-authored 25 publications receiving 274 citations.
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Journal ArticleDOI
Multispectroscopic and docking studies on the binding of chlorogenic acid isomers to human serum albumin: Effects of esteryl position on affinity.
TL;DR: Comparative studies on structure-affinity relationship contributed to the structural modification and design of phenolic food additives or new polyphenol-like drugs.
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In vitro investigation of the interaction between the hepatitis C virus drug sofosbuvir and human serum albumin through 1H NMR, molecular docking, and spectroscopic analyses
TL;DR: 1H NMR and conventional methods provided useful information to further elucidate the binding mechanisms of antiviral drugs with HSA and demonstrated that SOF was preferentially bound to site I of HSA.
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Molecular mechanism of the binding of 3,4,5-tri-O-caffeoylquinic acid to human serum albumin: Saturation transfer difference NMR, multi-spectroscopy, and docking studies.
TL;DR: The molecular mechanism of 3,4,5-triCQA in binding to HSA was clarified, and the findings are beneficial for the research on polyphenol-like drugs and antioxidants in foods or cosmetics.
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Binding modes of environmental endocrine disruptors to human serum albumin: insights from STD-NMR, ITC, spectroscopic and molecular docking studies.
Hongqin Yang,Yanmei Huang,Jiuyang Liu,Peixiao Tang,Qiaomei Sun,Xinnuo Xiong,Bin Tang,Jiawei He,Hui Li +8 more
TL;DR: STD-based binding studies indicated that both bisphenols are prone to attach to the binding site II in HSA, and spectroscopic results showed that BPB/BPE induces different degrees of microenvironmental and conformational changes to HSA.
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Studies of DNA-binding properties of lafutidine as adjuvant anticancer agent to calf thymus DNA using multi-spectroscopic approaches, NMR relaxation data, molecular docking and dynamical simulation
TL;DR: Fluorescence quenching and time-resolved fluorescence spectroscopy studies showed that the binding of LAF with ctDNA occurred through static quenched mechanism, resulting in the formation of a LAF-ctDNA complex.