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Yanna Zhao

Researcher at Liaocheng University

Publications -  61
Citations -  834

Yanna Zhao is an academic researcher from Liaocheng University. The author has contributed to research in topics: Chemistry & Drug carrier. The author has an hindex of 14, co-authored 50 publications receiving 434 citations. Previous affiliations of Yanna Zhao include Peking Union Medical College.

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Drug-binding albumins forming stabilized nanoparticles for co-delivery of paclitaxel and resveratrol: In vitro/in vivo evaluation and binding properties investigation

TL;DR: The novel paclitaxel/resveratrol co-loaded albumin nanoparticles (PTX/RES NPs) co-delivery system might be a promising strategy for combined anticancer therapy to overcome tumor drug resistance.
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Influence of polysaccharide as co-encapsulant on powder characteristics, survival and viability of microencapsulated Lactobacillus paracasei Lpc-37 by spray drying

TL;DR: In this paper, five polysaccharides were selected as co-encapsulant of skim milk based matrix and used for the microencapsulation of Lactobacillus paracasei Lpc-37 by spray drying.
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Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo.

TL;DR: Hemolytic evaluation indicated MTX/PGD NPs presented good blood compatibility, and the cytotoxicity of nanoparticles against breast cancer cells in vitro, biodistribution in tumor tissue, and antitumor efficacy in vivo were enhanced significantly compared to MTX injection.
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Enhanced Oral Bioavailability of Celecoxib Nanocrystalline Solid Dispersion based on Wet Media Milling Technique: Formulation, Optimization and In Vitro/In Vivo Evaluation.

TL;DR: In this paper, the authors developed and optimized CLX nanocrystalline (CLX-NC) solid dispersion prepared by the wet medium millingtechnique combined with lyophilization to enhance oral bioavailability.
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Effect of plasticizers on manufacturing ritonavir/copovidone solid dispersions via hot-melt extrusion: Preformulation, physicochemical characterization, and pharmacokinetics in rats

TL;DR: The in vitro release and the in vivo pharmacokinetics analyses both showed that RTV SD formulations using Span 20 or HSPC as plasticizer possessed better release profiles and bioavailability over RTV bulk powder but showed equal physicochemical characteristics compared to RTVSD formulations without plasticizer.