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Ye-Jin Cho
Researcher at Korea Research Institute of Bioscience and Biotechnology
Publications - 3
Citations - 101
Ye-Jin Cho is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Helix & Intrinsically disordered proteins. The author has an hindex of 3, co-authored 3 publications receiving 94 citations.
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Journal ArticleDOI
Understanding Pre-Structured Motifs (PreSMos) in Intrinsically Unfolded Proteins
Si-Hyung Lee,Do-Hyoung Kim,Joan J. Han,Eun-Ji Cha,Ji-Eun Lim,Ye-Jin Cho,Chewook Lee,Kyou-Hoon Han +7 more
TL;DR: A brief chronicle of Heteronuclear multidimensional NMR spectroscopy assisted with a stable isotope labeling technology studies on IUPs carried out over the past two decades is presented along with a discussion on the functional significance of PreSMos in Iups.
Journal ArticleDOI
A pre-structured helix in the intrinsically disordered 4EBP1.
Do-Hyoung Kim,Chewook Lee,Ye-Jin Cho,Si-Hyung Lee,Cha Eun Ji,Ji Eun Lim,T. M. Sabo,Christian Griesinger,Donghan Lee,Kyou-Hoon Han +9 more
TL;DR: It is shown that 4EBP1 is not completely unstructured, but contains a pre-structured helix, which contributed significantly to the proposal of the induced fit mechanism for target binding of intrinsically disordered proteins.
Journal ArticleDOI
The Mechanism of p53 Rescue by SUSP4.
Do-Hyoung Kim,Chewook Lee,Si-Hyung Lee,Kyungtae Kim,Joan J. Han,Joan J. Han,Eun-Ji Cha,Ji-Eun Lim,Ye-Jin Cho,Seung-Hee Hong,Kyou-Hoon Han +10 more
TL;DR: The discovery by NMR spectroscopy of a "p53 rescue motif" in SUSP4 that disrupts p53-mdm2 binding is presented, and this 29-residue motif is pre-populated with two transient helices connected by a hydrophobic linker.