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Ye-Ran Wang
Researcher at Third Military Medical University
Publications - 34
Citations - 1284
Ye-Ran Wang is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Medicine & Amyloid beta. The author has an hindex of 16, co-authored 29 publications receiving 809 citations. Previous affiliations of Ye-Ran Wang include University of South Australia.
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Journal ArticleDOI
Blood-derived amyloid-β protein induces Alzheimer's disease pathologies
Xian-Le Bu,Xiang Y,Jin Ws,Jun Wang,Lin-Lin Shen,Huang Zl,Zhang K,Yu-Hui Liu,Fan Zeng,Jiewei Liu,Jiewei Liu,Hao-Lun Sun,Zhen-Qian Zhuang,Si-Han Chen,Xiu-Qing Yao,Brian Giunta,Shan Yc,Jun Tan,Xiaowei Chen,Zhifang Dong,Hua-Dong Zhou,Xin-Fu Zhou,Weihong Song,Ye-Ran Wang +23 more
TL;DR: This study is the first to reveal that blood-derived Aβ can enter the brain, form the Aβ-related pathologies and induce functional deficits of neurons and provides evidence that supports the development of therapies for AD by targeting Aβ metabolism in both the brain and the periphery.
Journal ArticleDOI
Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits
Shu-Sheng Jiao,Xiu-Qing Yao,Yu-Hui Liu,Qing-Hua Wang,Fan Zeng,Jian-Jun Lu,Jia Liu,Chi Zhu,Lin-Lin Shen,Cheng-Hui Liu,Ye-Ran Wang,Gui-Hua Zeng,Ankit Parikh,Jia Chen,Chun-Rong Liang,Yang Xiang,Xian-Le Bu,Juan Deng,Jing Li,Juan Xu,Yue-Qin Zeng,Xiang Xu,Haiwei Xu,Jin-Hua Zhong,Hua-Dong Zhou,Xin-Fu Zhou,Xin-Fu Zhou,Yan-Jiang Wang +27 more
TL;DR: Edaravone, a free radical scavenger that is marketed for acute ischemic stroke, has a potent capacity of inhibiting Aβ aggregation and attenuating Aβ-induced oxidation in vitro and holds a promise as a therapeutic agent for AD by targeting multiple key pathways of the disease pathogenesis.
Journal ArticleDOI
The association between infectious burden and Parkinson's disease: A case-control study.
Xian-Le Bu,Xin Wang,Yang Xiang,Lin-Lin Shen,Qing-Hua Wang,Yu-Hui Liu,Shu-Sheng Jiao,Ye-Ran Wang,Hong-Yuan Cao,Xu Yi,Cheng-Hui Liu,Bo Deng,Xiu-Qing Yao,Zhi-Qiang Xu,Hua-Dong Zhou,Yan-Jiang Wang +15 more
TL;DR: The role of infection in the etiology of PD is supported as a composite serologic measure of exposure to common infectious pathogens as well as bacterial burden, viral burden and viral burden were independently associated with PD.
Journal ArticleDOI
One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study.
Yu-Hui Liu,Yang Chen,Qing-Hua Wang,Ling-Ru Wang,Li Jiang,Ying Yang,Xin Chen,Ying Li,Yuan Cen,Cheng Xu,Jie Zhu,Wei Li,Ye-Ran Wang,Li-Li Zhang,Juan Liu,Zhi-Qiang Xu,Yan-Jiang Wang +16 more
TL;DR: In this cohort study, COVID-19 survival was associated with an increase in risk of longitudinal cognitive decline, highlighting the importance of immediate measures to deal with this challenge.
Journal ArticleDOI
Sex Dimorphism Profile of Alzheimer's Disease-Type Pathologies in an APP/PS1 Mouse Model.
Shu-Sheng Jiao,Xian-Le Bu,Yu-Hui Liu,Chi Zhu,Qing-Hua Wang,Lin-Lin Shen,Cheng-Hui Liu,Ye-Ran Wang,Xiu-Qing Yao,Yan-Jiang Wang +9 more
TL;DR: A sex dimorphism in AD-type pathologic indices is described, suggesting that gender should be taken into account in designing studies involving these pathological indices and when interpreting the relevant findings in those studies.