Yi-Chang Liu

TL;DR: MALAT1 was overexpressed in patients with myeloma and may play a role in its pathogenesis and in addition, MALAT1 may serve as a molecular predictor of early progression.

TL;DR: The results suggest that the downregulated hPER3 expression in CML is correlated with the inactivation of hPER2 by methylation, and the methylated CpG frequencies differed significantly in patients at blastic crisis and at chronic phase.

TL;DR: Comparisons were made between the expression profiles of 9 circadian clock genes from peripheral blood mononuclear cells (PBMCs) and polymorphonuclear Cells (PMNs) and patients with chronic myeloid leukemia to indicate a possible association of the disrupted daily patterns of circadian clock gene expression with the pathogenesis of CML.

TL;DR: The results suggest deregulated expressions of circadian clock genes exist in GC and circadian rhythm disturbance may be associated with the development of GC.

TL;DR: This study has demonstrated that in the absence of p53 and p16, the induction of senescence by DOX was associated with upregulation of miR-375 and autophagy initiation, and the anti-proliferative function of mi R-375 is possibly exerted, at least in part, by targeting 14-3-3zeta and SP1 genes.