S
Sheng-Fung Lin
Researcher at Kaohsiung Medical University
Publications - 133
Citations - 2781
Sheng-Fung Lin is an academic researcher from Kaohsiung Medical University. The author has contributed to research in topics: Myeloid leukemia & Leukemia. The author has an hindex of 26, co-authored 130 publications receiving 2513 citations. Previous affiliations of Sheng-Fung Lin include I-Shou University & Fooyin University.
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Journal ArticleDOI
Altered expression of SIRT gene family in head and neck squamous cell carcinoma
Chi-Chih Lai,Pai-Mei Lin,Sheng-Fung Lin,Cheng-Hsien Hsu,Hsin-Ching Lin,Ming-Luen Hu,Cheng-Ming Hsu,Ming-Yu Yang +7 more
TL;DR: Real-time quantitative reverse transcription-polymerase chain reaction is used to investigate the expressions of the seven SIRT genes in human HNSCC tissues to assess the changes in cancerous and noncancerous parts and the correlation with different tumor behaviors and indicates that Sirt genes expression could help in the diagnosis and represent a prognostic biomarker in H NSCC.
Journal ArticleDOI
Disturbance of circadian gene expression in hepatocellular carcinoma.
Yueh-Min Lin,Julia H. Chang,Kun-Tu Yeh,Ming-Yu Yang,Ming-Yu Yang,Ta-Chih Liu,Sheng-Fung Lin,Wei-Wen Su,Jan-Gowth Chang +8 more
TL;DR: Downregulation of circadian genes results in disturbance of circadian rhythm in hepatocellular carcinoma which may disrupt the control of the central pacemaker and benefit selective survival of cancerous cells and promote carcinogenesis.
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MALAT1 long non-coding RNA is overexpressed in multiple myeloma and may serve as a marker to predict disease progression.
Shih-Feng Cho,Yuli Christine Chang,Chao-Sung Chang,Sheng-Fung Lin,Yi-Chang Liu,Hui-Hua Hsiao,Jan-Gowth Chang,Ta-Chih Liu +7 more
TL;DR: MALAT1 was overexpressed in patients with myeloma and may play a role in its pathogenesis and in addition, MALAT1 may serve as a molecular predictor of early progression.
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Downregulation of circadian clock genes in chronic myeloid leukemia: alternative methylation pattern of hPER3.
Ming-Yu Yang,Jan-Gowth Chang,Pai-Mei Lin,Kai-Ping Tang,Yen-Hsu Chen,Hugo You-Hsien Lin,Ta-Chih Liu,Hui-Hua Hsiao,Yi-Chang Liu,Sheng-Fung Lin +9 more
TL;DR: The results suggest that the downregulated hPER3 expression in CML is correlated with the inactivation of hPER2 by methylation, and the methylated CpG frequencies differed significantly in patients at blastic crisis and at chronic phase.
Journal ArticleDOI
Abnormal expression of period 1 (PER1) in endometrial carcinoma
Kun-Tu Yeh,Ming-Yu Yang,Ta-Chih Liu,Jui-Chang Chen,Wen-Ling Chan,Sheng-Fung Lin,Jan-Gowth Chang +6 more
TL;DR: The results suggest that down‐regulation of the PER1 gene disrupts the circadian rhythm, which may favour the survival of endometrial cancer cells.