Yen-Hsu Chen

TL;DR: A synthesis of information on current global trends in S. maltophilia pathogenicity as well as updated information on the molecular mechanisms contributing to its resistance to an array of antimicrobial agents is provided.

TL;DR: The current understanding of issues related to CRE is described and combination therapeutic strategies for CRE infections, including high-dose tigecycline, high- dose prolonged-infusion of carbapenem, and double carbapENem therapy are reviewed.

TL;DR: The lowered CLSI interpretive breakpoints for piperacillin-tazobactam, carbapenems, and some cephalosporins in 2011-2012 for Enterobacteriaceae resulted in an approximate 5% drop in susceptibility rates for each drug, with the exception of imipenem for which the susceptibility rate dropped from 99.4% according to 2010 criteria to 91.2%" according to 2011 criteria.

TL;DR: It is suggested that the decline of sepsis-induced autophagy contributes to the proximal tubular dysfunction, and maintenance of sufficient autophophagy prevents cell death.

TL;DR: The results suggest that the downregulated hPER3 expression in CML is correlated with the inactivation of hPER2 by methylation, and the methylated CpG frequencies differed significantly in patients at blastic crisis and at chronic phase.