Y
Yiling Shi
Researcher at Sir Run Run Shaw Hospital
Publications - 8
Citations - 483
Yiling Shi is an academic researcher from Sir Run Run Shaw Hospital. The author has contributed to research in topics: Exosome & Chondrocyte. The author has an hindex of 5, co-authored 5 publications receiving 201 citations.
Papers
More filters
Journal ArticleDOI
Desktop-stereolithography 3D printing of a radially oriented extracellular matrix/mesenchymal stem cell exosome bioink for osteochondral defect regeneration.
Pengfei Chen,Lin Zheng,Lin Zheng,Yiyun Wang,Min Tao,Ziang Xie,Chen Xia,Chenhui Gu,Jiaxin Chen,Pengcheng Qiu,Sheng Mei,Lei Ning,Yiling Shi,Chen Fang,Shunwu Fan,Xianfeng Lin +15 more
TL;DR: It is demonstrated that the 3D printed, radially oriented ECM/GelMA/exosome scaffold could be a promising strategy for early OA treatment.
Journal ArticleDOI
Mesenchymal stem cell-derived exosomes ameliorate intervertebral disc degeneration via anti-oxidant and anti-inflammatory effects.
Chen Xia,Zhongyou Zeng,Bin Fang,Min Tao,Chenhui Gu,Lin Zheng,Yiyun Wang,Yiling Shi,Chen Fang,Sheng Mei,Qi Chen,Juanjuan Zhao,Xianfeng Lin,Shunwu Fan,Yongming Jin,Pengfei Chen +15 more
TL;DR: The results confirmed that the NLRP3 inflammasome is an effective target for IVDD treatment and that the injection of exosomes could be a promising therapeutic strategy.
Journal ArticleDOI
Primary chondrocyte exosomes mediate osteoarthritis progression by regulating mitochondrion and immune reactivity.
Lin Zheng,Lin Zheng,Yiyun Wang,Pengcheng Qiu,Chen Xia,Yifan Fang,Sheng Mei,Chen Fang,Yiling Shi,Kaiwei Wu,Zhijun Chen,Shunwu Fan,Dengwei He,Xianfeng Lin,Pengfei Chen +14 more
TL;DR: D0 chondrocyte exosomes could restore mitochondrial dysfunction and polarize macrophage response toward an M2 phenotype and are demonstrated to be efficient in OA treatment.
Journal ArticleDOI
Decellularized cartilage as a prospective scaffold for cartilage repair.
Chen Xia,Sheng Mei,Chenhui Gu,Lin Zheng,Chen Fang,Yiling Shi,Kaiwei Wu,Tongtong Lu,Yongming Jin,Xianfeng Lin,Pengfei Chen +10 more
TL;DR: This review provides a comparative account of different cartilage defect therapies and provides a basis for the generation of decellularized cartilage scaffolds, thereby potentially promoting the possibility of de cellularization as a clinical therapeutic target.
Journal ArticleDOI
A cancellous bone matrix system with specific mineralisation degrees for mesenchymal stem cell differentiation and bone regeneration.
Shijie Liu,Yiyun Wang,Jian Wang,Pengcheng Qiu,Shengyu Wang,Yiling Shi,Mobai Li,Pengfei Chen,Xianfeng Lin,Xiangqian Fang +9 more
TL;DR: The present study shows that specific demineralised DCBM obtained under optimal conditions had superior properties to those of unmineralised or completely demin Mineralisation DCBM by promoting MSC osteogenic differentiation and initiating endochondral bone formation and de novo osteogenesis.