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Ying Xiong
Researcher at University of Virginia
Publications - 7
Citations - 119
Ying Xiong is an academic researcher from University of Virginia. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 2, co-authored 2 publications receiving 46 citations.
Papers
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Journal ArticleDOI
ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging.
TL;DR: A new family of ATP-independent bioluminescent reporters, which will have broad applications because of their ATP-independency, excellent biocompatibility, and superior in vivo sensitivity is engineered.
Journal ArticleDOI
Molecular Tools to Generate Reactive Oxygen Species in Biological Systems
TL;DR: A concise review of current molecular tools that can generate ROS in biological systems via either nongenetic or genetically encoded way is provided with the hope of broadening the applications of ROS generators in research and clinical settings.
Journal ArticleDOI
Engineering and exploiting synthetic allostery of NanoLuc luciferase
Zhongkun Guo,Rinky Parakra,Ying Xiong,Wayne A. Johnston,Patricia M. Walden,Selvakumar Edwardraja,Shayli Varasteh Moradi,Jacobus P.J. Ungerer,Hui-wang Ai,Jonathan J. Phillips,Kirill Alexandrov +10 more
TL;DR: In this paper , a synthetically allosteric version of circular permutated nanoLuc luciferase was constructed and activated through ligand-induced intramolecular non-covalent cyclisation.
Journal ArticleDOI
Engineering and exploiting synthetic allostery of NanoLuc luciferase
Zhongkun Guo,Rinky Parakra,Ying Xiong,Wayne A. Johnston,Patricia M. Walden,Selvakumar Edwardraja,Shayli Varasteh Moradi,Jacobus P.J. Ungerer,Hui-wang Ai,Jonathan J. Phillips,Kirill Alexandrov +10 more
TL;DR: In this paper , a synthetically allosteric version of circular permutated nanoLuc luciferase was constructed and activated through ligand-induced intramolecular non-covalent cyclisation.
Journal ArticleDOI
A luciferase prosubstrate and a red bioluminescent calcium indicator for imaging neuronal activity in mice
TL;DR: In this article , the authors developed a fluorescent prosubstrate with robust responsiveness to calcium ions (Ca2+) and appreciable emission above 600 nm for noninvasive mammalian imaging.