Yingjun Zhang

TL;DR: It is demonstrated that circARNT2 modulates cisplatin resistance through miR-155-5p/PDK1 pathway and may serve as a promising therapeutic target for overcoming cisPlatin resistance for HCC.

TL;DR: It is found that Hes1 was induced following brain injury, and that siRNA-mediated knockdown of Hes1 increased the cerebral infarction and worsened the neurological outcome, suggesting that Hes2 knockdown exacerbates ischemic stroke, and mechanistically, Hes1 knockdown promotes ER stress-induced apoptosis.

TL;DR: In this article , the authors studied the effect of amino acid supplements on aerobics athletes' muscle injury after endurance exercise using CT image analysis and found that the longer the exercise time and the more energy consumption, the more effective the branched-chain amino acids supplement will be.

TL;DR: A novel pathway that can contribute to oxaliplatin-induced NP is indicated, the Wnt3a/YTHDF1 to cytokine pathway, which upregulating YTHDF 1 functioned as the downstream of Wnt 3a signal and promoted the translation of TNF-α and IL-18 in oxali platin treated mice.

TL;DR: Intraperitoneal injection of galangin could inhibit the synthesis of alveolar inflammatory factors in theSD model of lung injury induced by LPS, reduce the degree of pathological injury of lung tissue, and improve the survival rate of the SD model.