Yini Wang

TL;DR: Interestingly, LHMCSs produce higher levels of pro-angiogenic, anti-inflammatory, and anti-apoptotic cytokines than those of bone marrow-derived MSCs, suggesting these cells may be a promising therapeutic source for liver diseases.

TL;DR: The genome-wide mapping of DNA methylation combined with hydroxymethylation in HBV-related HCC indicated that both 5-mC and 5-hmC epigenetic modifications play important roles in the regulation of HCC, and there may be some interconnections between them.

TL;DR: In this paper, the authors established the immortalized human stellate cells (HSC-Li) cell line using the simian virus 40 large T antigen (SV40LT) for applications in co-culturing with hepatocytes and HSC in vitro.

TL;DR: Results demonstrated the occurrence of marked metabolic disturbances during ALF and that integrated metabolomics analysis facilitates identification of biomarkers of disease, and showed a strong relationship with the extent of liver injury.

TL;DR: The method, which employs indirect co-culture with HSC-Li cells, can efficiently induce the differentiation of LPCs into functional hepatocytes, suggesting that this co- culture system can be a useful method for the efficient generation of functional hepatocyte-like cells.