Yiyang Sun

TL;DR: This review considers the physiologically achievable doses for a few of the best studied agents and summarizes the data derived from studies using these low concentrations in cell culture to conclude that each of the compounds shows an encouraging range of activities in vitro at concentrations which are likely to be physiologically relevant.

TL;DR: Results suggest that inhibition of STAT signalling and/or treatment with DIM may decrease invasiveness of bladder cancer and in combination with radiotherapy may be useful in overcoming such resistance.

TL;DR: It is shown that the dual inhibitor of ErbB receptors, lapatinib, enhances cytostatic and induces cytotoxic effects of GTC in two bladder cancer cell lines which differ with regard to expression levels of proteins taking part in the Erb B pathway.

TL;DR: In this article , the anti-heat stress and antioxidant effects of genistein and the underlying mechanisms, lipofuscin, reactive oxygen species (ROS), and survival under stress were first detected in Caenorhabditis elegans; then the localization and quantification of the fluorescent protein was determined by detecting the fluorescently labeled protein mutant strain; in addition, the aging-related mRNAs were detected by applying real-time fluorescent quantitative PCR in C. elegans.

TL;DR: In this paper , a transdermal drug delivery system containing losartan potassium (LP) and verapamil hydrochloride (VPH) was developed to enhance the antihypertensive effect.