Y
Yoav Sherman
Researcher at Hebrew University of Jerusalem
Publications - 32
Citations - 10850
Yoav Sherman is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Biopsy & Heparanase. The author has an hindex of 20, co-authored 32 publications receiving 10688 citations.
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Journal ArticleDOI
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.
TL;DR: The extent of tissue-PCD revealed by this method is considerably greater than apoptosis detected by nuclear morphology, and thus opens the way for a variety of studies.
Book ChapterDOI
Identification of dying cells--in situ staining.
TL;DR: The chapter develops a method that satisfies both criteria that is referred to as “terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end labeling (TUNEL)”, based on the observation that PCD is associated with DNA degradation.
Journal ArticleDOI
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
Immanuel Lerner,Esther Hermano,Eyal Zcharia,Dina Rodkin,Raanan Bulvik,Victoria Doviner,Ariel Rubinstein,Rivka Ishai-Michaeli,Ruth Atzmon,Yoav Sherman,Amichay Meirovitz,Tamar Peretz,Israel Vlodavsky,Michael Elkin +13 more
TL;DR: It is found that highly coordinated interactions between the epithelial compartment (contributing heparanase) and mucosal macrophages preserved chronic inflammatory conditions and created a tumor-promoting microenvironment characterized by enhanced NF-κB signaling and induction of STAT3.
Journal ArticleDOI
Immunostaining of lewis x in cells from voided urine, cytopathology and ultrasound for noninvasive detection of bladder tumors
TL;DR: Immunocytological evaluation of 2 consecutive voided urine specimens for the Lewis X antigen is the most sensitive method currently available for noninvasive detection of transitional cell tumors and may replace cystoscopy for detection of bladder cancer.
Journal ArticleDOI
A safety and tolerability study of differently-charged nanoparticles for local pulmonary drug delivery
Oshrat Harush-Frenkel,Maytal Bivas-Benita,Taher Nassar,Chaim Springer,Yoav Sherman,Avraham Avital,Yoram Altschuler,Jürgen Borlak,Simon Benita +8 more
TL;DR: Observations suggest that anionic PEG-PLA NPs are useful pulmonary drug carriers that should be considered as a promising therapeutic drug delivery system.