Y
Yoh Dobashi
Researcher at Jichi Medical University
Publications - 73
Citations - 2673
Yoh Dobashi is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Fluorescence in situ hybridization & Cancer. The author has an hindex of 28, co-authored 71 publications receiving 2408 citations. Previous affiliations of Yoh Dobashi include University of Yamanashi & International University of Health and Welfare.
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EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus.
Mitsuhiko Hanawa,Shioto Suzuki,Yoh Dobashi,Tetsu Yamane,Koji Kono,Nobuyuki Enomoto,Akishi Ooi,Akishi Ooi +7 more
TL;DR: In conclusion, anti‐EGFR therapies may be appropriate for patients with ESCC and combined analyses by immunohistochemistry/FISH would clarify aberrations in protein and gene function, and could help to identify those patients who may benefit from anti-EGFR therapy.
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Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers.
TL;DR: It is proposed that the new adjuvant chemotherapies could be directed to carcinomas of the biliary tract in which ErbB‐2 and EGFR are overexpressed.
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Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study
Akishi Ooi,Takuo Takehana,Xiaoling Li,Shioto Suzuki,Kazuyoshi Kunitomo,Hiroshi Iino,Hideki Fujii,Yasuhisa Takeda,Yoh Dobashi +8 more
TL;DR: Overexpression of HER-2 and EGFR were observed in only a small fraction of colorectal carcinomas, but were frequently accompanied by gene amplification.
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Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
TL;DR: Test whether oral intake of foods rich in polyamines (spermine and spermidine) suppresses age-associated pathology in aged mice demonstrated lower incidence of glomerulosclerosis and increased expression of senescence marker protein-30 in both kidney and liver compared to those fed the low polyamine chow.
Journal Article
Mammalian target of rapamycin: a central node of complex signaling cascades.
TL;DR: The mammalian target of rapamycin is a serine/threonine kinase that regulates cell growth and metabolism in response to diverse external stimuli and its roles in the physiology and pathology of human diseases, particularly, lung carcinomas are described.