A
Akishi Ooi
Researcher at Kanazawa University
Publications - 107
Citations - 4156
Akishi Ooi is an academic researcher from Kanazawa University. The author has contributed to research in topics: Cancer & Fluorescence in situ hybridization. The author has an hindex of 34, co-authored 107 publications receiving 3893 citations. Previous affiliations of Akishi Ooi include National Cancer Research Institute & University of Yamanashi.
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Journal ArticleDOI
EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus.
Mitsuhiko Hanawa,Shioto Suzuki,Yoh Dobashi,Tetsu Yamane,Koji Kono,Nobuyuki Enomoto,Akishi Ooi,Akishi Ooi +7 more
TL;DR: In conclusion, anti‐EGFR therapies may be appropriate for patients with ESCC and combined analyses by immunohistochemistry/FISH would clarify aberrations in protein and gene function, and could help to identify those patients who may benefit from anti-EGFR therapy.
Journal ArticleDOI
Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers.
TL;DR: It is proposed that the new adjuvant chemotherapies could be directed to carcinomas of the biliary tract in which ErbB‐2 and EGFR are overexpressed.
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Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immuno-sorbent assay.
Takuo Takehana,Kazuyoshi Kunitomo,Koji Kono,Fumiaki Kitahara,Hidehiko Iizuka,Yoshiro Matsumoto,Masayuki A. Fujino,Akishi Ooi +7 more
TL;DR: Patients having gastric adenocarcinoma with c‐erbB‐2 amplification are potential candidates for a new adjuvant therapy using humanized monoclonal antibody.
Journal ArticleDOI
Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study
Akishi Ooi,Takuo Takehana,Xiaoling Li,Shioto Suzuki,Kazuyoshi Kunitomo,Hiroshi Iino,Hideki Fujii,Yasuhisa Takeda,Yoh Dobashi +8 more
TL;DR: Overexpression of HER-2 and EGFR were observed in only a small fraction of colorectal carcinomas, but were frequently accompanied by gene amplification.
Journal ArticleDOI
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.
Toshio Munesue,Shigeru Yokoyama,Kazuhiko Nakamura,Ayyappan Anitha,Kazuo Yamada,Kenshi Hayashi,Tomoya Asaka,Hong-Xiang Liu,Duo Jin,Keita Koizumi,Mohammad Saharul Islam,Jian-Jun Huang,Wen Jie Ma,Uh-Hyun Kim,Sun Jun Kim,Keunwan Park,Dongsup Kim,Mitsuru Kikuchi,Yasuki Ono,Hideo Nakatani,Shiro Suda,Taishi Miyachi,Hirokazu Hirai,Alla B. Salmina,Yu A. Pichugina,Andrei A. Soumarokov,Nori Takei,Norio Mori,Masatsugu Tsujii,Toshiro Sugiyama,Kunimasa Yagi,Masakazu Yamagishi,Tsukasa Sasaki,Hidenori Yamasue,Nobumasa Kato,Ryota Hashimoto,Masako Taniike,Yutaka Hayashi,Jun-ichiro Hamada,Shioto Suzuki,Akishi Ooi,Mami Noda,Yuko Kamiyama,Mizuho A. Kido,Olga Lopatina,Minako Hashii,Sarwat Amina,Fabio Malavasi,Eric J. Huang,Jiasheng Zhang,Nobuaki Shimizu,Takeo Yoshikawa,Akihiro Matsushima,Yoshio Minabe,Haruhiro Higashida +54 more
TL;DR: The immunohistochemical expression of CD38 in the hypothalamus of post-mortem brains of non-ASD subjects is examined and it is found that CD38 was colocalized with OT in secretory neurons.