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Yolandy Lemmer
Researcher at Council of Scientific and Industrial Research
Publications - 30
Citations - 714
Yolandy Lemmer is an academic researcher from Council of Scientific and Industrial Research. The author has contributed to research in topics: Mycolic acid & Drug delivery. The author has an hindex of 8, co-authored 28 publications receiving 580 citations. Previous affiliations of Yolandy Lemmer include University of Pretoria & Council for Scientific and Industrial Research.
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Journal ArticleDOI
In vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systems
Boitumelo Semete,Laetitia Booysen,Laetitia Booysen,Yolandy Lemmer,Yolandy Lemmer,Lonji Kalombo,Lebogang Katata,Jan A. Verschoor,Hulda Swai +8 more
TL;DR: The toxic effects observed with various industrial nanoparticles is unlikely to be observed with particles made of PLGA when applied in the field of nanomedicine, and the biodistribution of these particles warrants surface modification to avoid particle accumulation in the liver.
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Blood Ketone Bodies and Breath Acetone Analysis and Their Correlations in Type 2 Diabetes Mellitus.
Valentine Saasa,Valentine Saasa,Mervyn Beukes,Yolandy Lemmer,Bonex W. Mwakikunga,Bonex W. Mwakikunga +5 more
TL;DR: This study assesses the efficacy of a simple breath test as a non-invasive means of diabetes monitoring in adults with type 2 diabetes mellitus and found a statistically significant relationship between breath acetone and blood acetoacetate.
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Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis.
Yolandy Lemmer,Lonji Kalombo,Ray-Dean Pietersen,Arwyn Tomos Jones,Boitumelo Semete-Makokotlela,Sandra Van Wyngaardt,Bathabile Ramalapa,Anton Stoltz,Bienyameen Baker,Jan A. Verschoor,Hulda Swai,Chantal de Chastellier +11 more
TL;DR: A new nanoformulation for use as an anti-TB drug delivery system consisting of incorporating mycobacterial cell wall mycolic acids as targeting ligands into a drug-encapsulating Poly dl-lactic-co-glycolic acid polymer (PLGA), via a double emulsion solvent evaporation technique.
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Polylactide-based Magnetic Spheres as Efficient Carriers for Anticancer Drug Delivery
Nikiwe Mhlanga,Nikiwe Mhlanga,Suprakas Sinha Ray,Suprakas Sinha Ray,Yolandy Lemmer,James Wesley-Smith +5 more
TL;DR: The synthesized polylactide spheres coencapsulating magnetic nanoparticles (MNPs, Fe3O4) and an anticancer drug (doxorubicin, DOX) have the potential for magnetic targeting of tumor cells to transform conventional methods.
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Structure-function relationships of the antigenicity of mycolic acids in tuberculosis patients.
Mervyn Beukes,Yolandy Lemmer,Madrey Deysel,Juma'a R. Al Dulayymi,Mark S. Baird,Gani Koza,Maximiliano M. Iglesias,Richard Rowles,Cornelia Theunissen,Johan Grooten,Gianna Toschi,Vanessa V. Roberts,Lynne A. Pilcher,Sandra Van Wyngaardt,Nsovo S. Mathebula,Mohammed Balogun,Anton Stoltz,Jan A. Verschoor +17 more
TL;DR: The potential to improve the specificity of serodiagnosis of TB with a defined single synthetic mycolic acid antigen from this set of antigens is argued against, although sensitivity may be facilitated by using a synthetic methoxy-mycolic acids.