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Yong Xie
Researcher at Chinese PLA General Hospital
Publications - 13
Citations - 491
Yong Xie is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Medicine & Bone remodeling. The author has an hindex of 8, co-authored 9 publications receiving 339 citations. Previous affiliations of Yong Xie include Peking Union Medical College.
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The roles of bone‐derived exosomes and exosomal microRNAs in regulating bone remodelling
TL;DR: The contents of bone‐derived exosomes and their functions in the regulatory processes of differentiation and communication of osteoclasts and osteoblasts are reviewed and microRNAs involved in the regulation of bone remodelling are highlighted.
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Protein content and functional characteristics of serum-purified exosomes from patients with colorectal cancer revealed by quantitative proteomics.
TL;DR: It is demonstrated that SPEs of CRC patients play a pivotal role in promoting the tumor invasiveness, but have minimal influence on putative alterations in tumor survival or proliferation.
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Cell Transplantation for Spinal Cord Injury: Tumorigenicity of Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cells
TL;DR: This review discusses the tumorigenicity of iPSC-derived NS/PCs focusing on the two different routes of tumorigeniability (teratomas and true tumors) and underlying mechanisms behind them, as well as possible solutions to circumvent them.
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Involvement of serum-derived exosomes of elderly patients with bone loss in failure of bone remodeling via alteration of exosomal bone-related proteins.
TL;DR: A quantitative proteomics analysis of exosomes purified from the serum of the elderly patients with osteoporosis/osteopenia and normal volunteers is presented, finding that the SDEs from aged normal volunteers might play a protective role in bone health through facilitating adhesion of bone cells and suppressing aging‐associated oxidative stress.
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Bench-to-bedside strategies for osteoporotic fracture: From osteoimmunology to mechanosensation
TL;DR: The molecular basis of osteoimmunology and bone mechanosensation in different healing phases of elderly osteoporotic fractures is highlighted, guiding perioperative management to alleviate the unfavorable effects of insufficient mechanical loading, high inflammatory levels and pathogen infection.