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Yong-Yuan Dai
Researcher at Southeast University
Publications - 9
Citations - 417
Yong-Yuan Dai is an academic researcher from Southeast University. The author has contributed to research in topics: Cancer cell & Drug resistance. The author has an hindex of 6, co-authored 9 publications receiving 388 citations.
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Journal ArticleDOI
The in vitro inhibition of multidrug resistance by combined nanoparticulate titanium dioxide and UV irradition.
TL;DR: It is observed that the combination of the nano-TiO2 and UV irradiation with the accompanying anticancer drug daunorubicin could provoke some considerable changes of the cell membrane of the target leukemia cells, which indicates that nano-O2 could not only increase the drug accumulation in target cancer cells, but also act as an effective anti-MDR agent to inhibit the relative drug resistance.
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The application of Fe3O4 nanoparticles in cancer research: a new strategy to inhibit drug resistance.
Xuemei Wang,Renyun Zhang,Chunhui Wu,Yong-Yuan Dai,Min Song,Sebastian Gutmann,Feng Gao,Gang Lv,Jingyuan Li,Xiaomao Li,Zhiqun Guan,Degang Fu,Baoan Chen +12 more
TL;DR: A novel strategy to inhibit the multidrug resistance of the targeted tumor cells by combining the unique properties of tetraheptylammonium capped Fe(3)O(4) magnetic nanoparticles with the drug accumulation of anticancer drug daunorubicin is explored.
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The Enhancement Effect of Gold Nanoparticles in Drug Delivery and as Biomarkers of Drug-Resistant Cancer Cells
Jingyuan Li,Xuemei Wang,Chunxia Wang,Baoan Chen,Yong-Yuan Dai,Renyun Zhang,Min Song,Gang Lv,Degang Fu +8 more
TL;DR: Observations indicate that the interaction between the functionalized Au NPs and biologically active molecules on the surface of leukemia cells may contribute the observed enhancement in cellular drug uptake.
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Synergistic enhancement effect of magnetic nanoparticles on anticancer drug accumulation in cancer cells
Renyun Zhang,Xuemei Wang,Chunhui Wu,Min Song,Jingyuan Li,Gang Lv,Jian Zhou,Chen Chen,Yong-Yuan Dai,Feng Gao,Degang Fu,Xiaomao Li,Zhiqun Guan,Baoan Chen +13 more
TL;DR: Observations indicate that the enhancement effect of Fe(3)O(4) nanoparticles is much stronger than that ofFe(2)O (3) and Ni nanoparticles, suggesting that nanoparticle surface chemistry and size as well as the unique properties of the magnetic nanoparticles themselves may contribute to the synergistic enhanced effect of the drug uptake of targeted cancer cells.
Journal ArticleDOI
Reversal in multidrug resistance by magnetic nanoparticle of Fe3O4 loaded with adriamycin and tetrandrine in K562/A02 leukemic cells.
Baoan Chen,Qian Sun,Xuemei Wang,Feng Gao,Yong-Yuan Dai,Yan Yin,Jia-Hua Ding,Chong Gao,Jian Cheng,Jing-Yuan Li,Xinchen Sun,Ning-Na Chen,Wen-Lin Xu,Hui-Ling Shen,Delong Liu +14 more
TL;DR: It is proposed that Fe3O4-MNPs loaded with ADM and Tet probably have synergetic effect on reversal in multidrug resistance and can enhance the effective accumulation of the drugs in K562/A02.