Yongjie Ma

TL;DR: The findings support a causative role of somatic tumour-related mutations of KRAS/BRAF in the overwhelming majority of brain and spinal arteriovenous malformations and implies the development of targeted therapies with RAS/RAF pathway inhibitors without the necessity of tissue genetic diagnosis.

TL;DR: Conservative treatment could not prevent occurrence of multiple episodes or rebleeding in patients, and microsurgery should be recommended as the preferred treatment strategy for SSEH.

TL;DR: Preoperative mALS score was associated with clinical improvement after adjusting for age, gender, duration of symptoms, location of fistula and treatment modality using unconditional logistic regression analysis (p<0.05).

TL;DR: Resection performed with an individualized surgical approach remains the primary therapeutic option in ISCCMs and predictors of outcomes after resection are identified.

TL;DR: The natural history of symptomatic spinal cord arteriovenous shunts is poor, especially in the early period after onset, and early intervention is thus recommended, and a differentiated treatment strategy is recommended.