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Yoshio Kuroki
Researcher at Sapporo Medical University
Publications - 177
Citations - 10921
Yoshio Kuroki is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Surfactant protein A & Collectin. The author has an hindex of 58, co-authored 177 publications receiving 10439 citations. Previous affiliations of Yoshio Kuroki include Sapporo University & RMIT University.
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Journal ArticleDOI
Serial Changes in Surfactant-associated Proteins in Lung and Serum before and after Onset of ARDS
Kelly E. Greene,Jo Rae Wright,Kenneth P. Steinberg,John T. Ruzinski,Ellen Caldwell,Wes B. Wong,William M. Hull,Jeffrey A. Whitsett,Toyoaki Akino,Yoshio Kuroki,Hisato Nagae,Leonard D. Hudson,Thomas R. Martin +12 more
TL;DR: The BAL SP-A and SP-D measurements can be used to classify patients as high or low risk for progression to ARDS and/or death after the onset of ARDS, and strategies to increase these surfactant proteins in the lungs of patients with ARDS could be useful to modify the onset or the course of AR DS.
Journal ArticleDOI
Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors
Norio Matsushima,Takanori Tanaka,Purevjav Enkhbayar,Tomoko Mikami,Tomoko Mikami,Masae Taga,Masae Taga,Keiko Yamada,Yoshio Kuroki +8 more
TL;DR: The super-repeat in the TLR7 family suggests strongly that "bacterial" and "typical" LRRs evolved from a common precursor and is inferred to play a key role in the structure and/or function of their TLRs.
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Direct binding of toll-like receptor 2 to zymosan, and zymosan-induced NF-κB activation and TNF-α secretion are down-regulated by lung collectin surfactant protein A
Morihito Sato,Hitomi Sano,Daisuke Iwaki,Kazumi Kudo,Masanori Konishi,Hiroki Takahashi,Toru Takahashi,Hitoshi Imaizumi,Yasufumi Asai,Yoshio Kuroki +9 more
TL;DR: An important role of SP-A is supported in controlling pulmonary inflammation caused by microbial pathogens as it down-regulates TLR2-mediated signaling and TNF-α secretion stimulated by zymosan.
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Serum surfactant proteins‐A and ‐D as biomarkers in idiopathic pulmonary fibrosis
Kelly E. Greene,Talmadge E. King,Yoshio Kuroki,B. Bucher-Bartelson,Gary W. Hunninghake,Lee S. Newman,Hisato Nagae,Robert J. Mason +7 more
TL;DR: The authors found that serum SP‐A and SP‐D levels were significantly elevated in patients with IPF and systemic sclerosis compared to sarcoidosis, beryllium disease and normal controls, and thatSP‐D correlated with radiographic abnormalities in patientswith IPF.
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Pulmonary surfactant protein D in sera and bronchoalveolar lavage fluids.
Yasuhito Honda,Yoshio Kuroki,Eiji Matsuura,Hisato Nagae,Hiroki Takahashi,Toyoaki Akino,Shosaku Abe +6 more
TL;DR: Measurement of SP-D in sera can provide an easily identifiable and useful clinical marker for the diagnosis of IPF, IPCD, and PAP, and can predict the disease activity of IPf and IPCd and the disease severity of PAP.