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Yoshitaka Fujii
Researcher at Nagoya City University
Publications - 306
Citations - 22300
Yoshitaka Fujii is an academic researcher from Nagoya City University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 59, co-authored 304 publications receiving 21040 citations.
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Journal ArticleDOI
EGFR R497K polymorphism is a favorable prognostic factor for advanced lung cancer.
Hidefumi Sasaki,Katsuhiro Okuda,Shigeki Shimizu,Minoru Takada,Masaaki Kawahara,Naoto Kitahara,Meinoshin Okumura,Akihide Matsumura,Keiji Iuchi,Tomoya Kawaguchi,Akihito Kubo,Osamu Kawano,Haruhiro Yukiue,Motoki Yano,Yoshitaka Fujii +14 more
TL;DR: R497KEGFR polymorphism might be associated with favorable prognosis of advanced lung cancers and correlated with chemosensitivity and no correlation existed between R497K EGFR genotype and clinico-pathological features, such as gender, smoking status, and pathological subtypes.
Journal ArticleDOI
PIK3CA mutation status in Japanese esophageal squamous cell carcinoma.
Ryota Mori,Hideyuki Ishiguro,Masahiro Kimura,Akira Mitsui,Hidefumi Sasaki,Keisuke Tomoda,Yoichiro Mori,Ryo Ogawa,Takeyasu Katada,Osamu Kawano,Koshiro Harada,Yoshitaka Fujii,Yoshiyuki Kuwabara +12 more
TL;DR: A PI3K inhibitor (LY294002) inhibited the growth of an esophageal cancer cell line with a PIK3CA mutation (E545K) in vitro and was found to reduce the proliferation of the esophagal cancercell line in vitro.
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Expression and prognostic roles of PABPC1 in esophageal cancer: correlation with tumor progression and postoperative survival.
Nobuhiro Takashima,Hideyuki Ishiguro,Yoshiyuki Kuwabara,Masahiro Kimura,Nobuhiro Haruki,Takuya Ando,Hiroki Kurehara,Nobuyoshi Sugito,Ryota Mori,Yoshitaka Fujii +9 more
TL;DR: In esophageal cancer, reduced expression of PABPC1 was correlated with local tumor progression and poor prognosis after surgery, and in ESCC patients with low PAB PC1 mRNA expression had a significantly shorter postoperative survival time.
Journal ArticleDOI
Thymoma with Dissemination: Efficacy of Macroscopic Total Resection of Disseminated Nodules
Motoki Yano,Hidefumi Sasaki,Haruhiro Yukiue,Osamu Kawano,Katsuhiro Okuda,Yu Hikosaka,Yoshitaka Fujii +6 more
TL;DR: Pursuing total resection for thymoma and disseminated nodules may be beneficial for stage IVThymoma, and the combination of preoperative steroid pulse therapy, macroscopictotal resection, and postoperative HTR may prolong the interval to relapse, but it did not lead to cure.
Journal ArticleDOI
Decreased expression of DFF45/ICAD is correlated with a poor prognosis in patients with esophageal carcinoma.
Shigeru Konishi,Hideyuki Ishiguro,Yasuyuki Shibata,Junzo Kudo,Yukio Terashita,Hironori Sugiura,Hiroshi Koyama,Masahiro Kimura,Atsushi Sato,Noriyuki Shinoda,Yoshiyuki Kuwabara,Yoshitaka Fujii +11 more
TL;DR: DNA fragmentation factor 45/inhibotor of caspase activated DNAse (ICAD) forms a complex with DFF40/CAD and inhibits its DNA cleaving function during apoptosis.