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Yoshitaka Fujii
Researcher at Nagoya City University
Publications - 306
Citations - 22300
Yoshitaka Fujii is an academic researcher from Nagoya City University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 59, co-authored 304 publications receiving 21040 citations.
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Journal ArticleDOI
Decreased perioxisome proliferator-activated receptor gamma gene expression was correlated with poor prognosis in patients with lung cancer.
Hidefumi Sasaki,Masayuki Tanahashi,Haruhiro Yukiue,Satoru Moiriyama,Yoshihiro Kobayashi,Yoshiaki Nakashima,Masahiro Kaji,Masanobu Kiriyama,Ichiro Fukai,Yosuke Yamakawa,Yoshitaka Fujii +10 more
TL;DR: Using the LightCycler RT-PCR assay, the determination of PPARgamma mRNA levels might provide a potential marker for treatment of lung cancer by PPARGamma agonist, however, further studies and a longer follow up are needed to confirm the impact of PPargamma in the biological behavior of the tumor.
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Decreased peroxisome proliferator-activated receptor gamma gene expression is correlated with poor prognosis in patients with esophageal cancer.
Yukio Terashita,Hidefumi Sasaki,Nobuhiro Haruki,Tadashi Nishiwaki,Hideyuki Ishiguro,Yasuyuki Shibata,Junzo Kudo,Shigeru Konishi,Joji Kato,Hiroshi Koyama,Masahiro Kimura,Atsushi Sato,Noriyuki Shinoda,Yoshiyuki Kuwabara,Yoshitaka Fujii +14 more
TL;DR: The mRNA expression level of PPAR gamma may be a marker of prognosis after operation in esophageal cancer patients and this work examined the correlation between the expression of PPar gamma mRNA with prognosis of esophagesia cancer patients.
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Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers.
Nobuhiro Haruki,Hiroko Saito,Tomoko Harano,Shuji Nomoto,Takao Takahashi,Hirotaka Osada,Yoshitaka Fujii,Takashi Takahashi +7 more
TL;DR: It is found that the BUB gene family members including BUB1, BUBR1 and BUB3 are not frequent targets for mitotic checkpoint defects in lung cancers, if present at all.
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A Correlation between EGFR Gene Mutation Status and Bronchioloalveolar Carcinoma Features in Japanese Patients with Adenocarcinoma
Hiroshi Haneda,Hidefumi Sasaki,Neal I. Lindeman,Osamu Kawano,Katsuhiko Endo,Eriko Suzuki,Shigeki Shimizu,Haruhiro Yukiue,Yoshihiro Kobayashi,Motoki Yano,Yoshitaka Fujii +10 more
TL;DR: Adenocarcinomas with BAC components in male non-smokers seem to predict the presence of EGFR mutation, and patient prognosis is predicted to be better than that of patients with adenOCarcinoma with Bac components with wild-type EGFR gene.
Journal ArticleDOI
p16INK4, pRB, p53 and cyclin D1 expression and hypermethylation of CDKN2 gene in thymoma and thymic carcinoma.
Hirohisa Hirabayashi,Yoshitaka Fujii,Masahiro Sakaguchi,Hisaichi Tanaka,Hyung Eun Yoon,Yosuke Komoto,Masahiro Inoue,Shinichiro Miyoshi,Hikaru Matsuda +8 more
TL;DR: The data suggest that, unlike other more common cancers, alteration of the p53 gene may not play a significant role in the tumorigenesis of thymoma, however, inactivation of p16INK4A and RB may play a role inThe progression ofThymoma and thymic carcinoma.