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Yoshitaka Nagahama
Researcher at National Institute for Basic Biology, Japan
Publications - 273
Citations - 13126
Yoshitaka Nagahama is an academic researcher from National Institute for Basic Biology, Japan. The author has contributed to research in topics: Oocyte & Complementary DNA. The author has an hindex of 63, co-authored 272 publications receiving 12523 citations. Previous affiliations of Yoshitaka Nagahama include Graduate University for Advanced Studies.
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Book ChapterDOI
6 The Functional Morphology of Teleost Gonads
TL;DR: This chapter discusses the functional morphology of teleost gonads and a two cell-type model involving thecal and granulosa cell layers has been proposed for the production of these two steroids for the first time in lower vertebrates.
Journal ArticleDOI
Foxl2 Up-Regulates Aromatase Gene Transcription in a Female-Specific Manner by Binding to the Promoter as Well as Interacting with Ad4 Binding Protein/Steroidogenic Factor 1
De Shou Wang,Tohru Kobayashi,Lin Yan Zhou,Lin Yan Zhou,Bindhu Paul-Prasanth,Shigeho Ijiri,Fumie Sakai,Kataaki Okubo,Ken Ichirou Morohashi,Yoshitaka Nagahama,Yoshitaka Nagahama +10 more
TL;DR: Results suggest that Foxl2 plays a decisive role in the ovarian differentiation of the Nile tilapia by regulating aromatase expression and possibly the entire steroidogenic pathway.
Book ChapterDOI
Regulation of oocyte growth and maturation in fish
TL;DR: Of considerable interest is the finding that MIH, unlike most steroid hormones, acts on its receptors at the surface of oocytes, and the mechanism of MIH-induced MPF activation in fish oocytes differs from that in Xenopus and starfish.
Journal ArticleDOI
A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus.
Minghui Li,Yun-Lv Sun,Jiue Zhao,Hongjuan Shi,Sheng Zeng,Kai Ye,Dongneng Jiang,Linyan Zhou,Lina Sun,Wenjing Tao,Yoshitaka Nagahama,Thomas D. Kocher,Deshou Wang +12 more
TL;DR: It is shown that amhy, a Y-specific duplicate of the anti-Müllerian hormone (amh) gene, induces male sex determination in Nile tilapia and the conserved roles of TGF-β signaling pathway in fish sex determination are highlighted.
Journal ArticleDOI
Identification of maturation-inducing steroid in a teleost, the amago salmon (Oncorhynchus rhodurus)☆
Yoshitaka Nagahama,Shinji Adachi +1 more
TL;DR: In this paper, the maturation-inducing activity of residues at various steps of purification was assessed by an in vitro germinal vesicle breakdown (GVBD) assay based on fully grown prophase-arrested folliculated oocytes of amago salmon.