Y
Yoshiyu Takeda
Researcher at Kanazawa University
Publications - 178
Citations - 4109
Yoshiyu Takeda is an academic researcher from Kanazawa University. The author has contributed to research in topics: Aldosterone & Primary aldosteronism. The author has an hindex of 32, co-authored 159 publications receiving 3579 citations.
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Journal ArticleDOI
Vascular aldosterone. Biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cells.
TL;DR: Direct evidence is shown that vascular cells per se are aldosteronogenic, possessing their own system that responds to the steroid, providing the starting point for a novel understanding of the molecular basis of vascular remodeling and hypertension.
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Reassessment of the cutoff values of waist circumference and visceral fat area for identifying Japanese subjects at risk for the metabolic syndrome.
Rie Oka,Junji Kobayashi,Kunimasa Yagi,Hideji Tanii,Susumu Miyamoto,Akimichi Asano,Tomomi Hagishita,Mika Mori,Tadashi Moriuchi,Makoto Kobayashi,Shouji Katsuda,Masa-aki Kawashiri,Atsushi Nohara,Yoshiyu Takeda,Hiroshi Mabuchi,Masakazu Yamagishi +15 more
TL;DR: Setting the cutoff points of WC and VFA lower values in women than in men for the definition of central obesity is needed to identify the subjects with MetS in Japanese, as in other Asian populations.
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Cardiac Aldosterone Production in Genetically Hypertensive Rats
TL;DR: It is suggested that the rat heart produces ald testosterone and that endogenous cardiac aldosterone may affect cardiac function and hypertrophy in hypertension in rats.
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Sodium-induced cardiac aldosterone synthesis causes cardiac hypertrophy.
TL;DR: It is suggested that high sodium intake increases cardiac aldosterone synthesis, which may contribute to cardiac hypertrophy independently of the circulating renin-angiotensin-aldosterone system.
Journal ArticleDOI
Vascular Aldosterone in Genetically Hypertensive Rats
Yoshiyu Takeda,Isamu Miyamori,Satoru Inaba,Kenji Furukawa,Haruhiko Hatakeyama,Takashi Yoneda,Hiroshi Mabuchi,Ryoyu Takeda +7 more
TL;DR: Vascular aldosterone contributes to the pathophysiology of hypertension in SHRSP in the early stage, and levels of cytochrome P450aldo and mineralocorticoid receptor mRNA in the vasculature were significantly increased compared with those in age-matched WKY.