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Young-Chul Choi
Researcher at University of Pennsylvania
Publications - 1
Citations - 518
Young-Chul Choi is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Gene & Gene targeting. The author has an hindex of 1, co-authored 1 publications receiving 475 citations.
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Haploinsufficiency of protamine-1 or -2 causes infertility in mice.
Chunghee Cho,William D. Willis,Eugenia H. Goulding,Haesook Jung-Ha,Young-Chul Choi,Norman B. Hecht,Edward M. Eddy +6 more
TL;DR: It is found that a decrease in the amount of either protamine disrupts nuclear formation, processing of protamine-2 and normal sperm function, and that haploinsufficiency caused by a mutation in one allele of Prm1 or Prm2 prevents genetic transmission of both mutant and wild-type alleles.