Y
Young Jack Lee
Researcher at National Institutes of Health
Publications - 28
Citations - 1837
Young Jack Lee is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Clinical trial & Selection (genetic algorithm). The author has an hindex of 14, co-authored 28 publications receiving 1769 citations. Previous affiliations of Young Jack Lee include Hanyang University.
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Journal ArticleDOI
Phenobarbital for Febrile Seizures — Effects on Intelligence and on Seizure Recurrence
Jacqueline R. Farwell,Young Jack Lee,Deborah Hirtz,Stephen Sulzbacher,Jonas H. Ellenberg,Karin B. Nelson +5 more
TL;DR: It is concluded that phenobarbital depresses cognitive performance in children treated for febrile seizures and that this disadvantage may outlast the administration of the drug by several months and is not offset by the benefit of seizure prevention.
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Minimum effective dose of folic acid for food fortification to prevent neural-tube defects
Sean Daly,James L. Mills,Anne M. Molloy,Mary Conley,Young Jack Lee,Peadar N. Kirke,Donald G. Weir,John M. Scott +7 more
TL;DR: A fortification programme that delivered 400 micrograms folic acid daily to women would protect against NTD, but at the expense of unnecessarily high exposure for many people.
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Analysis of clinical trials by treatment actually received: is it really an option?
TL;DR: The problem of the definition of actual treatment is investigated in the context of a recent clinical trial, which provided results that were at times inconsistent or counter-intuitive, and which neither helped to confirm nor further explain the intention to treat analysis.
Journal ArticleDOI
Methylenetetrahydrofolate reductase thermolabile variant and oral clefts.
James L. Mills,Peadar N. Kirke,Anne M. Molloy,Helen Burke,Mary Conley,Young Jack Lee,Philip Mayne,Donald G. Weir,John M. Scott +8 more
TL;DR: In the Irish population homozygosity for the common folate-related polymorphism associated with thermolabile MTHFR is significantly more frequent in those with isolated cleft palate, and could be etiologically important.
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Prognostic factors in Burkitt's lymphoma: importance of total tumor burden.
Ian T. Magrath,Young Jack Lee,Thomas Anderson,Werner Henle,John L. Ziegler,Richard Simon,Philip S. Schein +6 more
TL;DR: It is concluded that the tumor burden is the single most important prognostic factor in Burkitt's lymphoma, and that this is reflected directly by LDH and UA concentrations, and probably indirectly by anti‐EA titer.