J
John M. Scott
Researcher at Trinity College, Dublin
Publications - 297
Citations - 20009
John M. Scott is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Population & Homocysteine. The author has an hindex of 71, co-authored 297 publications receiving 19125 citations. Previous affiliations of John M. Scott include University College Dublin & Northern Health and Social Care Trust.
Papers
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Journal ArticleDOI
Facts and Recommendations about Total Homocysteine Determinations: An Expert Opinion
Helga Refsum,A. David Smith,Per Magne Ueland,Ebba Nexo,Robert Clarke,Joseph McPartlin,Carole Johnston,Frode Engbaek,Jörn Schneede,Catherine McPartlin,John M. Scott +10 more
TL;DR: The purpose of this review is to provide an international expert opinion on the practical aspects of total homocysteine determinations in clinical practice and in the research setting and on the relevance of total Homocystinuria measurements as diagnostic or screening tests in several target populations.
Journal ArticleDOI
Folate levels and neural tube defects. Implications for prevention.
TL;DR: In this article, the reduction in neural tube defect (NTD) cases that would be expected under two different strategies to raise folate levels was calculated using case-control data.
Journal ArticleDOI
Homocysteine metabolism in pregnancies complicated by neural-tube defects
TL;DR: The study shows that an abnormality in homocysteine metabolism, apparently related to methionine synthase, is present in many women who give birth to children with neural-tube defects and suggests that the most effective periconceptional prophylaxis to prevent neural- tube defects may require B 12 as well as folic acid.
Journal ArticleDOI
Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects.
TL;DR: Plasma folate and plasma B12 were independent risk factors for NTDs, suggesting that the enzyme methionine synthase is involved directly or indirectly in the aetiology.
Book ChapterDOI
Microbiological assay for serum, plasma, and red cell folate using cryopreserved, microtiter plate method.
Anne M. Molloy,John M. Scott +1 more
TL;DR: This chapter presents microbiological assay for serum, plasma, and red cell folate, using cryopreserved, microtiter plate method, and the final working standard concentration of 500 ng/liter is presented.