Natural biodegradable polymers based nano-formulations for drug delivery: A review.

Guar gum and its composites as potential materials for diverse applications: A review

Biodegradable and conducting hydrogels based on Guar gum polysaccharide for antibacterial and dye removal applications.

Polyelectrolyte complexes formed between chitosan (CS) and anionic polymers have attracted increasing interest in drug delivery. In this study, CS is copolymerized with hypromellose via a coupling reagent-mediated approach to form a water-soluble, nontoxic CS derivative, namely hypromellose-graft-CS (HC), which is subsequently complexed with carboxymethylcellulose (CMC) to generate a polyampholytic hydrogel. When compared with conventional CS, HC is highly water-soluble across a wide pH range, and has a substantially higher pH buffering capacity to provide a pH-stable environment for delivery of drugs. In addition, the polyelectrolyte complex of HC exhibits a drug encapsulation efficiency of over 90% in all drugs tested, which is 1–2 fold higher than the efficiency attainable by the polyelectrolyte complex of conventional CS, with a 2–3 fold longer duration of sustained drug release. Our results indicate that as a novel polymer, HC has excellent promise for future pharmaceutical applications.

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Yousra Gul

Papers

Graft polymerization of guar gum with acryl amide irradiated by microwaves for colonic drug delivery.