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Yu Chuan Chien
Researcher at China Medical University (Taiwan)
Publications - 9
Citations - 151
Yu Chuan Chien is an academic researcher from China Medical University (Taiwan). The author has contributed to research in topics: Docosahexaenoic acid & Randomized controlled trial. The author has an hindex of 5, co-authored 8 publications receiving 79 citations.
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Journal ArticleDOI
Melatonergic agonist regulates circadian clock genes and peripheral inflammatory and neuroplasticity markers in patients with depression and anxiety.
Senthil Kumaran Satyanarayanan,Yu Chuan Chien,Jane Pei-Chen Chang,Shih Yi Huang,Ta-Wei Guu,Huanxing Su,Kuan-Pin Su,Kuan-Pin Su +7 more
TL;DR: RMT treatment is able to restore phase-shifted melatonin markers, normalized the altered expression of the circadian genes, the levels of inflammatory cytokines and neurotrophins in patients with insomnia comorbid anxiety and depression.
Journal ArticleDOI
Omega-3 polyunsaturated fatty acids in cardiovascular diseases comorbid major depressive disorder - Results from a randomized controlled trial.
Jane Pei-Chen Chang,Shih-Sheng Chang,Hui Ting Yang,Hui Ting Chen,Yu Chuan Chien,Bo Yang,Huanxing Su,Kuan-Pin Su,Kuan-Pin Su +8 more
TL;DR: N-3 PUFAs supplementation may provide a treatment option for a subpopulation of patients with CVDs comorbid MDD, and when stratified with depression severity, n-3PUfAs supplementation improved core depression symptoms in the very severe MDD group.
Journal ArticleDOI
Clinical Efficacy and Biological Regulations of ω–3 PUFA-Derived Endocannabinoids in Major Depressive Disorder
Bo Yang,Lin Lin,Richard P. Bazinet,Yu Chuan Chien,Jane Pei-Chen Chang,Senthil Kumaran Satyanarayanan,Huanxing Su,Kuan-Pin Su +7 more
TL;DR: Treatments enriched with EPA increased plasma EPEA levels, which was positively associated with clinical remission, which may suggest that levels of plasma E PEA play a potential novel endogenous therapeutic target in MDD.
Journal ArticleDOI
The efficacy of omega-3 fatty acids for depressive symptoms among pregnant women in Japan and Taiwan: A randomized, double-blind, placebo-controlled trial (SYNCHRO; NCT01948596)
Daisuke Nishi,Daisuke Nishi,Kuan-Pin Su,Kuan-Pin Su,Kentaro Usuda,Jane Pei-Chen Chang,Jane Pei-Chen Chang,Yi Ju Chiang,Hui Ting Chen,Yu Chuan Chien,Tai Wei Guu,Emi Okazaki,Kei Hamazaki,Ryoko Susukida,Naoki Nakaya,Toshimasa Sone,Yo Sano,Hiroe Ito,Keiichi Isaka,Yoshiyuki Tachibana,Shinji Tanigaki,Tomo Suzuki,Kenji Hashimoto,Tomohito Hamazaki,Yutaka Matsuoka +24 more
TL;DR: The aim of this double-blind randomized controlled trial (RCT) was to determine the efficacy of this moderate daily dose of omega-3 PUFA supplementation for depressive symptoms among pregnant women in Japan and Taiwan.
Journal ArticleDOI
Anti-Oxidative Effects of Melatonin Receptor Agonist and Omega-3 Polyunsaturated Fatty Acids in Neuronal SH-SY5Y Cells: Deciphering Synergic Effects on Anti-Depressant Mechanisms.
Senthil Kumaran Satyanarayanan,Yin Hwa Shih,Yin Hwa Shih,Yu Chuan Chien,Shih Yi Huang,Piotr Gałecki,Siegfried Kasper,Jane Pei-Chen Chang,Jane Pei-Chen Chang,Kuan-Pin Su,Kuan-Pin Su +10 more
TL;DR: The results demonstrated that RMT and EPA synergistically provide effective neuroprotective, anti-oxidative/inflammatory effect against oxidative stress, and provides pre-clinical evidence to conduct future clinical trials of using n-3 PUFAs/RMT combination in depressive disorders.