Yu Koyama

TL;DR: A new water channel (aquaporin-8, gene symbol AQP8) was isolated from rat pancreas and liver by homology cloning and ribonuclease protection assay showed intense expression of the gene in pancrea and liver, less intense in colon and salivary gland, and negligible in other organs.

TL;DR: Findings may indicate that water crosses the epithelial layer through these water channels, suggesting a possible role of the transcellular route for water intake or outlet in the gastrointestinal tract.

TL;DR: Although AQP10 belongs to the AQP subfamily, which has been characterized by permeability to water and neutral solutes such as urea and Glycerol, it was not permeable to urea nor glycerol.

TL;DR: Aquaporin (AQP) 5 gene was recently isolated from salivary gland and identified as a member of the AQP family and a role of AQP5 in water transport to prevent dehydration or to secrete watery products in these tissues is suggested.

TL;DR: The localization of immunoreactive aquaporin-8 and expression of the mRNA indicated functions for this water channel in the secretion of bile and pancreatic juice, the secretion or absorption of water in the colon and jejunum, and the maturation or liberation of spermatogenic cells in the testis.