Y
Yu Zhao
Researcher at National University of Singapore
Publications - 113
Citations - 4902
Yu Zhao is an academic researcher from National University of Singapore. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 35, co-authored 97 publications receiving 3708 citations. Previous affiliations of Yu Zhao include Boston College & Massachusetts Institute of Technology.
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Highly Z-selective metathesis homocoupling of terminal olefins.
TL;DR: It is proposed that high Z-selectivity is achieved because a large aryloxide only allows metallacyclobutanes to form that contain adjacent cis substituents and because isomerization of Z-product to E-product can be slow in that same steric environment.
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Construction of Nine-Membered Heterocycles through Palladium-Catalyzed Formal [5+4] Cycloaddition
TL;DR: Under palladium catalysis, the reaction of N-tosyl azadienes and substituted vinylethylene carbonates (VECs) proceeds smoothly to produce benzofuran-fused heterocycles in uniformly high efficiency.
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Stereoselective 1,6-Conjugate Addition/Annulation of para-Quinone Methides with Vinyl Epoxides/Cyclopropanes
Chao Ma,Yuan Huang,Yu Zhao +2 more
TL;DR: In this article, an unprecedented formal [3 + 2] cycloaddition of para-quinone methides with vinyl epoxides/cyclopropanes is presented, which can deliver a wide range of spiro[4.5]decanes in high efficiency and stereoselectivity.
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Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis by Pd-Catalysis and Rearrangement via Transannular Bond Formation
Zi-Qiang Rong,Li-Cheng Yang,Song Liu,Zhaoyuan Yu,Ya-Nong Wang,Zher Yin Tan,Rui-Zhi Huang,Yu Lan,Yu Zhao +8 more
TL;DR: The first enantioselective formal [5+4] cycloaddition is realized under palladium catalysis to deliver benzofuran-fused nine-membered rings in excellent efficiency and stereoselectivity.
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Catalytic enantioselective amination of alcohols by the use of borrowing hydrogen methodology: cooperative catalysis by iridium and a chiral phosphoric acid.
TL;DR: This work examined various transition-metal complexes supported by chiral ligands known for asymmetric hydrogenation reactions, in combination with chiral Brønsted acids, which proved essential for the formation of the imine intermediate and the transfer-hydrogenation step.